83 results
To provide clinical management and, if required, treatment to subjects who at their concluding HPV-015 study visit displayed normal cervical cytology but tested positive for oncogenic HPV infection or who were pregnant at their concluding visit of…
To establish biomarkers in nipple aspirate fluid, follow them in time and link them to breast cancer development at its earliest stage in women at high risk for breast cancer. Threshold values of biomarkers will be determined that point to a…
(1) to measure the forces resulting from typical mammographic compressions by decomposing them into a component exercised on the breast and a component exercised on adjacent body structures, (2) to determine how the proportion of these two…
To assess the effects of vaginal prolapse surgery on microcirculatory parameters measured in the vaginal wall with the use of incident dark field (IDF) imaging (Cytocam).
Biobanking of testicular biopsies from azoospermic men undergoing testicular sperm extraction (TESE)
Biobanking of a testis biopsy from men with azoospermia who undergo a TESE procedure to allow investigation for understanding the etiology of male infertility, research about normal and aberrant male gamete formation in its natural environment of…
During this feasibility study will be analysed if endometrial cells by using tampons can be obtained during surveillance of women with Lynch syndrome and first degree relatives at 50% risk of the gene mutation who get annual surveillance in the…
In breast-conserving surgery, there is evidence that approximately 30% of women receive a suboptimal or poor aesthetic outcome; however there is currently no standardised method of identifying these women.The PICTURE project aims to address these…
Our primary objective is to determine whether testing for molecular markers, i.e. hrHPV, methylationmarkers , i.a. CADM1/MAL and combinations thereof, yields a higher sensitivity and specificity for the detection of CIN2/3 or cancer after treatment…
The aim of this project is to develop a comprehensive EORTC questionnaire for assessing sexual health for male and female patients with cancer. Given the lack of a sexual health related measure that can be used in clinical trials and in clinical…
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…
To preserve testicular tissue of young boys with cancer for possible autologous transplantation in the future if infertility has become apparent.
The PICTURE project aims to address these issues by providing objective tools, tailored to the individual patient, to predict the aesthetic outcome of local treatment. Using a combination of 3D photography and routinely acquired radiological images…
The aim of the study is to determine whether prenatal and current exposure to environmental chemicals is associated with developmental outcome in adolescents. We will investigate whether this exposure is associated with the thyroid hormone…
1. To examine and describe the vaginal microcirculation in patients with VA in comparison to patients without VA2. To examine and describe the effect of treatment with local oestrogen on the vaginal microcirculation.
To identify molecular alterations associated with cervical tumorigenesis, that could be used as biomarker for improving detection and differentiation between cervical cancer, cervical intraepithelial neoplasia and normal cervical tissue.
The aim of the proposed research is to assess, using multimodal fMRI, both functional (BOLD responses) and structural (white matter) cerebral characteristics of the human IELT. In turn, this could provide specific novel (neocortical) targets in the…
To explore the effect of Eligard® on the following prostate cancer biomarkers:• Testosterone in serum• Prostate Specific Antigen (PSA) in serum• Prostate Cancer Antigen (PCA3 score) in urine • PSA mRNA in blood/PBMC• PCA3 mRNA in blood/PBMC• TMPRSS2…
The overall aim of the present work is to evaluate the individual role of androgens and estrogens on brain function in the human with a focus on cognition. Both clinical models give us the opportunity to evaluate cognitive functions and brain…
Aim of the hereby proposed study is to evaluate the DA for FP on its effectiveness compared to treatment as usual (TAU) regarding outcomes of decision making and decision making processes. Primary outcome is decisional coflict.
This study will be conducted to determine the overall hr-HPV agreement between self-sampled cervicovaginal smear (Evalyn Brush) and physician-obtained samples taken by a trained physician (liquid based cervical smear) in a screening population. The…