22 results
To establish biomarkers in nipple aspirate fluid, follow them in time and link them to breast cancer development at its earliest stage in women at high risk for breast cancer. Threshold values of biomarkers will be determined that point to a…
To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.
Objective: The primary objectives of this study are comparing the duration of recurrence free survival following completion of treatment between the 2 study arms. Secondary objectives of this study involves toxicity and morbidity, quality of life,…
* To demonstrate efficacy of the candidate vaccine in the prevention of (1) persistent infection (6-month definition) with HPV-16 or HPV-18 (by polymerase chain reaction [PCR]) and/or (2) histopathologically-confirmed CIN1+ associated with HPV-16 or…
Evaluation of the capacity of a HPV 16 peptide vaccine to install a long term HPV-specific T cell response, to define the importance of a booster vaccine after 1 year, the induction of Cytotoxic T lymphocyte (CTL) immunity against HPV16E6 and E7 and…
1) To assess whether galactosemia women with ovarian failure are able to produce estradiol after exogenous (normally bioactive) FSH and LH gift 2) To characterize FSH glycan structures
This study aims to reveal whether vaccination of women with HPV 16+ cervical intraepithelial neoplasia not only results in a strong systemic T-cell response, but also endows these T-cells with the capacity to infiltrate HPV16-induced lesions.…
The primary aim of the phase I part of this study is to establish the safety profile and to determine the maximum tolerated dose of capecitabine combined with Re-188-HEDP.The primary aim of the phase II part of this study is to obtain insight in the…
To study the effect of peginterferon alpha and ribavirin on spermatozoa
Objectives to explore: :1-whether kinase activities can be detected in lymphocytes derived from cancer patients, using a peptide array or a phosphopeptide capture SELDI-TOF MS assay.2-how many cells are needed for the generation of a kinase activity…
To quantify the motion of the seminal vesicles.
1. Success of maintenance of erection in men with ED.and 2. Improvement of their female partner*s sexual quality of life.
The aims of this prospective study are to investigate:1a: Changes in menopausal symptoms and biochemical changes as result of PBSO in premenopausal women.1b: Changes in menopausal symptoms and biochemical changes as result of PBSO in postmenopausal…
We intend to employ an ex vivo model of human implantation to study the factors involved in successful implantation. By linking parameters of successful implantation with embryo quality markers, we aim to improve embryo selection and IVF outcomes.…
Aim: By conducting a retrospective evaluative follow up study we attempt to answer the following question: Is(full) recovery of pelvic pain in women associated with illness related attributions and cognitions about their condition?
To determine the performance characteristics (specificity, sensitivity, and positive and negative predictive values) of the PCA3 Assay using prostate biopsy as the reference method in men who are scheduled for a repeat prostate biopsy after a…
We will assess the correlation between the incidence of early pregnancy loss and the successrate of ART in women with unexplained infertility. We will also investigate the difference in the incidence of early pregnancy loss in women with unexplained…
Primary Objective: To identify maternal and embryonic factors associated with recurrent implantation failure, by prospectively• comparing embryo and endometrium secretion cytokine profiles of women with recurrent implantation failure versus women…
- Assess the feasibility of the nipple aspiration procedure- Gain experience in methods and techniques of nipple aspiration - Identify factors that are associated with the fluid yielding status of nonlactating women- Assess the discomfort…
The purpose of the study is to establish normative values of the size of the testis measured by ultrasonography in childhood, through puberty till adulthood. (0-18 years)