36 results
We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…
The current research is focused on finding a method that is able to better stratify the patients. A possible method could be to study PSA in more detail, specifically the modifications which are present on the protein. One of these modifications is…
We aim to demonstrate that robot-assisted laparoscopic radical hysterectomy is non-inferior to conventional laparotomy in recurrence free survival of patients with early stage cervical cancer (stage 1B1, 1B2 and 2A1).
Progesterone for Breast Development in Trans Women; Assessment of effects and safety -a pilot trial-
To explore the effects on breast development of addition of progesterone to the treatment with estradiol in trans women after vaginoplasty or orchiectomy. Secondary objectives include safety and patient satisfaction, mood, and sleep.
To study if a blended personalized periconception lifestyle care approach aimed at women with a high risk for pregnancy complications who are contemplating pregnancy or already pregnant (*12 weeks) can significantly reduce Lifestyle Risk Score.
To determine the feasibility of additional flushing of the fallopian tubes with Lipiodol after tubal testing with methylene-blue during THL.
To measure saturation and desaturation of the cavernosal tissue with a cutaneousplaced penile sensor, before and during full rigidity. To validate discriminatingsensor-readings between flaccid state and full rigidity of the penis. To explore the…
To determine if stimulated salivation during the biodistribution of PSMA-ligands causes a significant increase in the accumulation in salivary glands
To address the role of free thiols in males of couples seeking infertility treatment.
The main goal of this study is to analyse the influence of the menstrual cycle on NK cell receptor variability.
To investigate that low-dose HDR-brachytherapy of prostate cancer will make from an immunologically *cold* (no T-cell infiltrations) prostate cancer an immunologically *hot* (CD4 and CD8-cell infiltrations) tumor.
The overall study aim is to determine the efficacy rate of complete ablation for the most promising types of thermal ablation (RFA, MWA or CA) technique for patients with early stage breast cancer (cT1N0M0) without an extensive component of DCIS (…
Primary Objective: The aim of this study is to compare if an online consultation with diagnostic testing during a fertility workup, is as effective as a regular consultation in terms of patient centeredness, shared decision making and costs.
In this pilot study will focus on the question whether it is possible to detect and distinguish specific immune cells which are previously found in endometriotic tissue, in , macroscopically non-affected peritoneum, peritoneal fluid, peripheral…
Investigation of maintenance of erectile function after MR-guided radiotherapy with neurovascular sparing in patients with localized prostate cancer.
Primary objective: to study the (cost) effectiveness of applying the 4DryField barrier on the uterine scar after a caesarean delivery, in the prevention of adhesions, niche development and related gynecological symptoms. Secondary objectives: to…
Primary Objective: To study the feasibility of Velocity Selective Arterial Spin Labeling as a non-invasive technique for breast cancer screening by comparing image quality with DCE-MRI.Secondary Objectives: Comparing tumor characteristics and…
1. To compare pembrolizumab plus enzalutamide plus ADT versus placebo plus enzalutamide plus ADT with respect to radiographic progression free survival (rPFS)2. To compare pembrolizumab plus enzalutamide plus ADT versus placebp plus enzalutamide…
This protocol describes a framework that will be used to create multiple studies, which are based on the secondary objectives. The outcomes of the studies together will provide more insight in the primary objective. Primary Objective: Investigate…
The primary objective of this study is to investigate whether usual care combined with CBT improves QoL in patients undergoing surgery for endometriosis compared to usual care only. Secondary objectives are to investigate whether pain intensity,…