36 results
Primary Objective: The aim of this study is to compare if an online consultation with diagnostic testing during a fertility workup, is as effective as a regular consultation in terms of patient centeredness, shared decision making and costs.
This protocol describes a framework that will be used to create multiple studies, which are based on the secondary objectives. The outcomes of the studies together will provide more insight in the primary objective. Primary Objective: Investigate…
This study has been transitioned to CTIS with ID 2023-509881-39-00 check the CTIS register for the current data. The aim of this study is to evaluate the difference in the fraction of patients that have disease progression within 6 months after…
The primary objective of this study is to investigate whether usual care combined with CBT improves QoL in patients undergoing surgery for endometriosis compared to usual care only. Secondary objectives are to investigate whether pain intensity,…
To address the role of free thiols in males of couples seeking infertility treatment.
The overall study aim is to determine the efficacy rate of complete ablation for the most promising types of thermal ablation (RFA, MWA or CA) technique for patients with early stage breast cancer (cT1N0M0) without an extensive component of DCIS (…
The current research is focused on finding a method that is able to better stratify the patients. A possible method could be to study PSA in more detail, specifically the modifications which are present on the protein. One of these modifications is…
This study has been transitioned to CTIS with ID 2023-504998-20-00 check the CTIS register for the current data. - To compare the effect of capivasertib + abiraterone relative to placebo + abiraterone by assessment of radiographic progression-free…
This study aims to create an indication of the effect size during and after adherence to the low FODMAP diet to calculate a sample size for a future RCT on this subject.
Patients will be included in 3 prospective cohorts, cohort A, B, C and 1 retrospective cohort, cohort 0. Cohort A: The primary objective of cohort A is to show that by implementing a standard infrastructure all newly diagnosed girls with cancer (or…
Primary objective: To evaluate the safety, tolerability, and maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) of investigational therapies in subjects with metastatic castration-resistant prostate cancer (mCRPC).Secondary objective:*…
to demonstrate that the ProSpace, when properly inserted between the prostate and the rectum is safe and effective in reducing the volume of the rectum receiving greater or equal to 70 Gy (VRectum70) by means of IMRT in prostate cancer patients…
The hormonal range of LH, FSH, AMH, inhibin B, testosterone and estradiol in girls with TS during the minipuberty and the relation of the hormone serum levels with the karyotype.
This study has been transitioned to CTIS with ID 2023-506365-64-00 check the CTIS register for the current data. The purpose of this study is to investigate if niraparib added to a standard treatment (consisting of abiraterone acetate plus…
The goal of this pilot study is to 1. Investigate the feasibility of the lymphatic mapping procedure in locally advanced cervical cancer 2. Study the agreement of the lymphatic map with the radiotherapy treatment plan. Are all lymph nodes at risk…
To determine the long-term (cost)effectiveness of Magnetic Resonance image guided High Intensity Focused Ultrasound (MR-HIFU) compared to standard (minimally) invasive fibroid care in-cluding UAE, myomectomy and hysterectomy.
Primary Objective:• To compare the progression-free survival (PFS) of patients randomized to mirvetuximab soravtansine (MIRV) vs. Investigator*s choice of chemotherapy (IC Chemo) Key Secondary Objectives:• To compare the objective response rate (ORR…
Improving fertility preservation counseling by gynaecologists by providing more insight in important ascpects for patients regarding fertility preservation trough autotransplantation of cryopreserved ovarian tissue.
The primary aim of the present study is to investigate whether current standard treatment for PID is clinically effective in patients in whom Mycoplasma genitalium (MG) is present. A secondary aim of the study is to asses whether this treatment is…
In this project, we hypothesize that presence of genetic variants associated with earlier age of natural menopause might be involved in diminished responsiveness of the ovaries to exogenous FSH stimulation during IVF treatment. Furthermore, we aim…