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Image guided surgery for tumor detection in solid cancers using the pH activated micellar probe ONM-100: The SHINe study

The main purpose is to investigate the safety, pharmacokinetics and feasibility of ONM-100 as an intra-operative optical tracer to detect tumors and metastatic lymph nodes in solid cancers. Moreover, the study will investigate the optimal dose of…

Towards implementation of on-line MRI-guided radiation therapy in breast cancer patients

To develop and evaluate an adaptive MRI-only workflow for the MR-linac treatment in breast cancer patients eligible for APBI, regional lymph node irradiation or a radiotherapy boost on tumor positive lymph nodes. Furthermore, to investigate whether…

Development of a more sensitive method to predict breast cancer recurrence after 5-years of endocrine treatment making use of diagnostic leukapheresis to detect circulating tumor cells

We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…