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Clinical validation of transrectal multiparametric ultrasound imaging strategy (PCaVision) for the detection of clinically significant prostate cancer: a European head-to-head comparison with the MRI-based strategy in primary diagnosis and in an active surveillance population

The primary objective is to demonstrate non-inferiority of the detection rate of clinically significant prostate cancer (defined as GG>=2) in targeted biopsies based on PGaVision imaging (PCaVision pathway) in comparison with the detection…

Two-fraction Ultra-hypofractionated Radiotherapy with Focal Boost for low- and intermediate risk, localized prostate cancer (TURBO):phase II, randomized controlled clinical trial

To assess non-inferiority of treating patients with localized, intermediate risk prostate cancer in two fractions of 12 Gray (Gy) with a boost to the gross tumor volume of 13.5 Gy per fraction in 8 days, as compared to standard care (36.25 Gy in…