97 results
Objective 1: To prospectively evaluate the utility of C-FLOW monitor to examine status of regional CBF and reperfusion in patients presenting with acute anterior circulation ischemic stroke syndrome. Objective 2: To assess the feasibility,…
This protocol is the next step in development of a reproducible technique for the quantification of CBF using simultaneous ultrasound at the internal carotid artery. We hypothesize that simultaneous measurement of the contrast signal in the internal…
To ascertain the hypothesis that T-cell inflammation in the vascular wall of an unruptured intracranial aneurysm can be accurately detected with 18F-IL2 PET (proof-of-concept).
To assess if information about aortic calcification obtained from routine preoperative ultra low-dose chest CT reconstructed with IR lowers the postoperative stroke rate in patients undergoing heart surgery by optimizing surgical strategy compared…
To assess the sensitivity and negative predictive values of D-dimer- and FXIII activation peptide (AP-FXIII) values in order to exclude to exclude CVT in patients with clinical suspicion of CVT.
Determining the diagnostic value of CTA in patients with acute headache and normal neurological examination and head CT by performing a prospective study. Charting patient characteristics in order to more purposefully apply the CTA and avoid…
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
In this study we aim to investigate the presence of CAN in diabetic patients scheduled for elective major abdominal and thoracic surgery and its relation with perioperative hemodynamic changes.
1. To determine the diagnostic accuracy, in terms of detecting a vascular malformation, of CTA, MRI/MRA, DSA, or combinations thereof in patients with ICH?2. To find out which test or combination of tests is most effective for the detection of…
The primary objective is to investigate which balance and reaching performance measures - estimated using body-mounted sensing - correlate with frequently used clinical assessments of balance and motor function, while measuring stroke patients in a…
Assessment of the diagnostic accuracy of CTA for the detection of vasospasm after SAH in comparison to TCD.
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic HCHWA-D disease carriers, in order to find a *biomarker* for disease stage and progression.
to evaluate the feasibility, time-course and association with clinical manifestations of the pulsatility index (PI) in patients with cerebral venous thrombosis.
To investigate whether the amount of TiMas containing brain specific proteins, correlates with functional outcome and infarct size in patients with acute ischemic stroke. And, to study the kinetics of the tissue macrophages and to compare these data…
the main objective of this study is to evaluate the ability and reproducibility of high-resolution 3 Tesla MR imaging to visualise intracranial arteries and intracranial atherosclerotic disease in patients with previous TIA or ischemic stroke.
There are two objectives for this study.1. To investigate the frequency of somatosensory deficits in the early and chronic stage of stroke patients.2. To understand the nature and the neuroanatomical correlates of specific higher order somatosensory…
The primary objective will be to assess whether cerebrovascular reactivity is impaired in patients with steno-occlusive disease of the vertebrobasilar artery .
To asses the agreement of KNN volumetry on 1,5 and 3 Tesla MRI.
The aim of the study is to answer the following questions:On which measures do patients with aphasia seem to differ from controls matched on age and country of origin, in the analysis of the spontaneous speech according to the guidelines of the ASTA…
The objective of this study is to assess the influence of the executed motor paradigm on associations between brain activity patterns and recovery after stroke. In addition the role of spinal cord integrity in recovery will be assessed.