57 results
The aim of this study is to analyse the analgetic effect of a local injection in the lateral femoral cutaneous nerve ( LFCN) with methylprednisolone/lidocaine (M/L) after localisation through elektro stimulation VS placebo. In this trial we hope to…
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
The primary objective of this study is to investigate attenuation of pain and sensory thresholds during dorsal root ganglion stimulation using QST. The secondary objectives of this study are to investigate 1) To assess changes in pain intensity (NRS…
The aim of this study is to further explore ultrasonographic abnormalities of peripheral nerves in patients with NF and their relation with symptoms, findings in neurological examination and electrophysiological characteristics.Primary objective:…
To study whether flavoprotein imaging can be used to diagnose painful polyneuropathy, we first need to investigate whether a reproducible and validated flavoprotein signal can be obtained on the second fingertip of healthy subjects.
To investigate the potential value of magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) on a 3 Tesla and 7 Tesla MRI system and ultrasound (US) to visualize the peripheral nerves and muscles in the forearm to diagnose MMN and ALS…
The purpose of this study is to see if we can predict which patients with CTS are eligible for an injection, and which should be directly referred to a surgeon. This to shorten the period of the patient's symptoms and to save healthcare costs.
The primary objective of this study is to investigate whether SCS combined with best (drug) treatment as usual (TAU) leads to clinically significant (>=50%) pain relief in patients suffering from moderate-to-severe PDP in the lower limbs…
The primary aim of the proposed multi-site study is to determine if the CRPS Severity Score can be used as a clinical bedside tool to monitor CRPS change in symptoms over time, specifically progression or regression. Various interventions will occur…
Assess the natural course of UNE in patients with mild to moderate symptoms by using clinical, electrophysiological and ultrasonographic data
To study the quantitative and qualitative relationship between a heat stimulus and the vasomotor response in healthy subjects and to determine the feasibility of this measurement setup for patients.
The main objective of this study is to provide insight in the morbidity with regards to the upper extremity surrounding the radial access route in percutaneous coronary interventions.Secondary objectives are the following:• To provide insight at the…
First, we investigate the attention-bias for pain signals that chronic pain patients (CPP) are suggested to have. Second, we investigate whether the chronicity of pain is related to faster learning and slower *unlearning* of new associations between…
To evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic LRS.
Objective: The aim of this study is to validate the Dutch versions of the PainDETECT questionnaire PD-Q and the *Douleur neuropathique en 4 questions* (DN4) for use in primary and specialist medical care settings for patients with LBP and NSP and…
Objective: This study design aims to give insight in the reproducibility of a new method of testing static and dynamic stimuli with Von Frey monofilaments, as well as acquiring information on the ability to localise stimuli in CRPS patients
To evaluate and implement the cutaneous electrical stimulation pain model at the Kendle Clinical Pharmacology Unit.To investigate whether these human experimental pain models can discriminate the analgesic effects of a single oral dose of Tramadol…
The ulitmate goal of the current study will be the presentation of a specific minimum core set of outcome measures to be used in future clinical and follow-up studies in patients with autoimmune mediated polyneuropathies.
The present study aims to assess the long-term outcome of patients who suffered from GBS during childhood. This outcome at least six months after diagnosis will be determined in patients previously seen at the department of Paediatric Neurology of…
1) The objective of this study is to confirm the hypothesis that SCS leads to pain relief as indicated by the results of two former pilot studies (Tesfaye et al. 1996 and Vos et al. 2008). 2) The practical feasibility of the test procedures…