Search for a trial

Value of surgical decompression of the nerves of the lower extremities in patients with painful diabetic polyneuropathy: Lower Extremity Nerve entrapment Study (LENS)

To evaluate the effect of surgical decompression of the nerves in the lower extremities in patients with painful diabetic neuropathy.

Effect of Spinal Cord Stimulation in Painful Diabetic Polyneuropathy: a multicenter Randomised Controlled Trial (PDP study)

The primary objective of this study is to investigate whether SCS combined with best (drug) treatment as usual (TAU) leads to clinically significant (>=50%) pain relief in patients suffering from moderate-to-severe PDP in the lower limbs…

Frozen Gloves in the prevention of polyneuropathy

The goal of this study is to examine the effect of cooling on neuropathy in the hands of patients who are treated with Paclitaxel, Docetaxel en Oxaliplatin. Patients who will be included in the study are those who start with chemotherapy. The…

Ulnar neuropathy at the elbow: short-term follow-up using clinical, electrodiagnostic and sonographic data

Assess the natural course of UNE in patients with mild to moderate symptoms by using clinical, electrophysiological and ultrasonographic data

Correlation of joint stiffness and stiffness of the skin and the prevelation of carpal tunnel syndrome (CTS).

To clarify the aetiology of CTS and prognostic factors for the development of CTS.

Non-contact heat evoked vasomotor response in healthy subjects

To study the quantitative and qualitative relationship between a heat stimulus and the vasomotor response in healthy subjects and to determine the feasibility of this measurement setup for patients.

Dendritic cell and B cell response to Campylobacter predisposing to Guillain-Barré syndrome.

The primary objective is to determine whether the DC/B-cell response to C. jejuni LOS differs in (ex-)patients with C. jejuni-related GBS compared to healthy controls. Secondly, we aim to define the variation in DC/B-cell response to C. jejuni LOS…

A multicenter, Single arm, Open label study of The Repeated Administration Of Qutenza For The Treatment Of Peripheral Neuropathic Pain.

The purpose of the study is to assess the safety and efficacy of repeated treatments of QUTENZA in subjects with peripheral neuropathic pain.

A Phase I, Single-Centre, Randomized, Double-Blind, Placebo Controlled, Multiple Dose Study to Evaluate the Effect of tedalinab on ECG parameters, CNS Function and Pain Perception in Healthy Subjects.

Evaluate the effect of tedalinab on ECG parameters, CNS Function and Pain Perception in Healthy Subjects.

Development of a nociceptive test battery - acute pain tests

Primary Objective* Investigate the feasibility, applicability, safety, tolerability, and reproducibility of nociceptive tests in healthy volunteers.Secondary Objectives* Investigation of confounding factors including fear of pain, mood, age and…

Validation study: a newly developed neuropathic pain Heat-Capsaicin-Warmth (HCW) sensitization model.

Primary:Part I:- to determine the effects of gabapentin and remifentanil on the evoked area of hyperalgesia, area of allodynia, pinprick hyperalgesia and background pain using a newly developed HCW sensitization modelPart II: - to determine…

Neuropathic Pain: development and validation of a clinical prediction rule

Primary: to develop and validate a clinical prediction rule to predict a favourable or unfavourable disease course for NP patients, therewith enabling tailor made treatments for NP patients.Secondary: determine prevalence of clinical signs of NP in…