94 results
The main objective is to assess whether Bediol (containing THC and CBD) co-treatment will reduce opioid side effects in chronic pain patients. A secondary objective will be that Bediol is superior to oxycodone in the relief of chronic fibromyalgia…
The goal of this study is to examine the effectiveness of an online psychological intervention based on Acceptance and Commitment Therapy (ACT) in a Randomized Controlled Trial (RCT) and compared to a treatment-as-usual control condition (TAU). We…
Use Magneto-encephalography (MEG) to image the cortical and thalamic effects that underlie the analgesic effects of SCS for chronic pain patients. To analyse the differences in cortical and thalamic activity between SCS ON and SCS OFF.
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP. The second objective is to determine the predictive value of a DOBRET to identify sustained responders.
Primary objective:To evaluate the efficacy of ION-682884, based on the change from Baseline in serum Transthyretin (TTR) concentration, modified Neuropathy Impairment Score +7 (mNIS+7), and Norfolk Quality of Life Questionnaire-Diabetic Neuropathy (…
The objective of this study is to assess the efficacy and cost-effectiveness of a treatment strategy starting with surgical intervention compared to a starting treatment with steroid injection.
Determining the feasibility of EVNS performed at home by the patient and/or caregiver, after instruction from the podiatrist.
The primary research question of the trial is to assess whether foot drop, caused by peroneal nerve entrapment in adult patients* recovers better within 9 months after decompressive surgery compared to prolonged standard conservative treatment. *…
The main objective is that a cognitive behavioral intervention for patients with SFN will have a positive effect on disability and quality of life.
Primary Objective: to show a reduction in eGFR decline in patients treated with LCP tacrolimus compared to IR tacrolimus. Secondary objectives will include investigating the potential decline in other known side effects of calcineurin inhibitors i.e…
The primary objectives:Period 1:The primary objective is to assess the long-term (up to 2 years) safety and tolerability of two doses of PXT3003.Period 2:For patients continuing after V9, the main objective will be to offer patients the opportunity…
The primary aim is to investigate the effect of neuromodulation (via UCon) on the symptoms of patients with PGAD. The hypothesis we want to test is whether neuromodulation of the DGN reduces the severity of symptoms of PGAD.
The primary objective is to determine whether in patients with CIPN pain, treatment with Qutenza has the same effect as treatment with duloxetine
Evaluation of the (cost-)effectiveness of surgical decompression of compressed lower extremity nerves (LEND surgery) compared to patients 'treated' with conventional best care.
To evaluate the effect of peripheral nerve decompression surgery in patients with headache caused by entrapment neuropathy,comparing it to conventional treatment.
Primary Objective- To evaluate the feasibility and test-retest variability of nerve excitability threshold tracking - To investigate the sensitivity of nerve excitability measures to detect the effects of mexiletine- To investigate the sensitivity…
Primary:To determine the efficacy of AG10 in the treatment of subjects with symptomatic transthyretin amyloid polyneuropathy (ATTR-PN) by evaluating the difference between the AG10 and placebo groups in Modified Neuropathy Impairment Score + 7 (mNIS…
The objective of this study is to investigate if low frequency stimulation with a DRG stimulator effects peripheral blood blow in patients with CRPS and vasomotor disturbances. The secondary goal is to investigate if the frequency with the best…
To demonstrate that SCS is capable of treating otherwise refractory neuropathic pain after chemotherapy / radiotherapy.