223 results
As none of the proposed experimental conditions have been executed with chronic pain patients, our main objective is to determine the sensitivity of the experimental conditions. Besides, we investigate the attention-bias for pain signals that…
First, we investigate the attention-bias for pain signals that chronic pain patients (CPP) are suggested to have. Second, we investigate whether the chronicity of pain is related to faster learning and slower *unlearning* of new associations between…
To determine whether the ulnar nerve*s cross-sectional area decreases over time after endoscopic in situ neurolysis, and whether this correlates with electrophysiological findings.
To measure the PK of ARA290 when given in de SQ form
To determine, in patients registered at our hospital having CRPS (types I) at the leg, the percentage of patients having clinical features compatible with SFN and compared to the unaffected leg (in unilateral cases) to determine possible focal or…
What is the long-term clinical benefit of best medical practice with and without adjunctive SCS Therapy in patients with chronic diabetic neuropathic pain?
To evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic LRS.
1) The primary objective of this pilot study is to compare the clonal composition of the TCR repertoire in anterior fascicular sural nerve biopsies with the TCR repertoire in peripheral blood of CIDP patients with active disease in order to identify…
Main object Is there a reduction of the acute peripheral neuropathy complaints of patients with advanced or metastatic colorectal cancer due to the infusion of heated oxaliplatin?Does the quality of life of these patients improve?Secondary objectThe…
The objective of this study is to develop a resistance training intervention that improves mobility and quality of life in diabetic patients. It is also our intension to achieve a better understanding of the relation between diabetic neuropathy and…
To investigate the relation between different autonomic function tests in critically ill patients.
Primary objective:The primary objective of this study is to compare the short-term and long-term efficacy of neurolysis and a conservative strategy for relieving symptoms in mild cases of UNE. Secondary objectives:- VAS score for paresthesias- VAS…
The primary objective is to determine whether the DC/B-cell response to C. jejuni LOS differs in (ex-)patients with C. jejuni-related GBS compared to healthy controls. Secondly, we aim to define the variation in DC/B-cell response to C. jejuni LOS…
The purpose of the study is to assess the safety and efficacy of repeated treatments of QUTENZA in subjects with peripheral neuropathic pain.
The study has three objectives. Firstly, we will study the safety and tolerability of the drug after the administration of both single and multiple doses of the drug. Secondly, we will study the speed at which the drug is absorbed in the body, as…
At time of publication
Objective: The aim of this study is to validate the Dutch versions of the PainDETECT questionnaire PD-Q and the *Douleur neuropathique en 4 questions* (DN4) for use in primary and specialist medical care settings for patients with LBP and NSP and…
The primary objective is to establish the neuroprotective efficacy of NAC against cisplatin-induced neurotoxicity. Mainly the sensory neuronal guidance will be assessed before and after treatment with cisplatin in a group of patients receiving NAC…
Aim of this study was to assess the long term effects of the babysitter procedure in patients with proximal nerve injury.
Objective: This study design aims to give insight in the reproducibility of a new method of testing static and dynamic stimuli with Von Frey monofilaments, as well as acquiring information on the ability to localise stimuli in CRPS patients