23 results
The main objective is to investigate if the sensation of children with an upper OBPL is diminished. Both children that were treated conservatively as children that were surgically treated with nerve surgery in early infancy.The primary research…
Primary Objective: Evaluate the functional integrity of the nociceptive system after percutaneous cervical chordotomy using Laser Evoked Potentials Secondary Objective(s): change in opioid consumption after percutaneous cervical chordotomy using a…
Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…
The purpose of the this study is to evaluate the prognostic capabilities of biomarkers in CSF in patients with SCI.
Aim of the study is to evaluate if the optical tissue stylet technology can discriminate tissues that are relevant to recognize for interventional pain procedures.
The primary objective of this study is to investigate the potential of the photonic needle to discriminate between correct and incorrect placement of the needle tip in the target area of the procedure (M4 - tissue), as confirmed by contrast-enhanced…
Investigating the relationship between post traumatic stress disorder, psychological factors and pain in Spinal Cord Injured patients.
Gain insight in the anatomy and organisation of the sacral plexus in children with NB and congenital spinal or sacral anomalies. Possible findings can be compared with the results of the healthy subjects, in order to be able to relate findings to…
Reserach to the observation of neurophysiologic pain mechanisms and the differences between healthy subjects and pain patients.
The purpose of the this study is to evaluate the prognostic capabilities of DWI and biomarkers in CSF in patients with SCI.
The aim of this research is to examine the effects of changes in proprioceptive and visual information on balance control in WAD sufferers. Although clinical experience suggests more effective balance control due to elevated proprioceptive…
To visualize the affected nerve roots using DTI with tractography. The anatomy and organisation of the nerves on the level of the lumbar disc herniation will be visualized. Diffusion parameters as FA, ADC, AD, and RD could provide valuable…
In the literature the effectiveness of the anterior cervical discectomy is measured using subjective validated questionnaires.It would be an important improvement if it is possible to detect the inflammatory process of the dorsal root ganglion with…
To monitor and describe the natural motor learning of handrim wheelchair propulsion during usual care in a Dutch spinal cord injury rehabilitation center. Motor learning is operationalized as change in mechanical efficiency, propulsion technique and…
The purpose of this study is to explore the usefulness of various neurophysiological tests regarding accuracy and feasibility for the detection of spinal cord ischemia. In particular, to find a diagnostic test which is acceptable for the…
Neuroplast has scheduled to start in 2018 with a phase I and a phase II/III clinical trial with patients with a traumatic spinal cord injury to confirm the efficacy and safety in humans. A GMP license to produce clinical grade Neuro-Cells is…
To investigate the influence of body posture on the measurement cervical sagittal balance parameters.
Primary Objective: The primary objective of this study is to map cerebral glucose metabolism of patients diagnosed with FBSS in an effort to elucidate imaging biomarkers that could predict the effectiveness of SCS treatment. Secondary Objectives:…
To determine the presence or absence of central sensitisation in patients with CLBPr and to determine the effect of segmental nerve interventions on central sensitisation.
In this pilot, we aim to improve the detection rate of LM by using the CellSearch technique quantifying circulating tumor cells (CTCs) in cerebrospinal fluid (CSF, i.e. CSFCTs) and compare this with the current standard of care; namely cytological…