24 results
To show whether Active C disc prosthesis is more effective than anterior discectomy with or without interbody fusion 1 year after surgery. Moreover, the incidence of adjacent disc degeneration will be evaluated 5 years after surgery.
The study will excist of two experiments. The first experiment is a two week overnight electrical stimulation program and in the second experiment subjects will be stimulated for 4 months.With these two experiments we wish to answer the following…
The general accepted Hueter-Volkmann law describes the inverse relation between compressive forces on the physis and the rate of physeal growth. So compression decreases and tension increases longitudinal growth. The observed deformities in patients…
The primary goal of this study to investigate the long term functional and radiological outcome of those patients that underwent a cervical laminectomy in the treatment of a cervical spondylotic myelopathy.The secondary goal is to determine those…
To assess whether there is less peri-operative pain and a faster post operative recovery.
The primary objective of this study is to identify the brain changes following peripheral nerve injury and establishing their functional role in recovery. The secondary objective is to evaluate new fMRI methodology in a patient population.
The main purpose of this study is to evaluate the effects of surface electrical stimulation of the gluteal and hamstring muscles on sitting pressure under the buttocks during daily life (3 hours). A second purpose is to compare the effects of only…
The aim of this study is to investigate if adaptation could cause a change in the valuations of the patient*s health state and other health states over time.
The purpose of this study is to investigate the acute effects of gluteal and hamstring ES on femoral artery blood flow, skin vascular function and energy expenditure using ES shorts as a simplistic non-invasive method of ES.
Primary Objective: To evaluate potential changes in body composition and REE after NMES therapy at home for 12 weeks.We hypothesize that NMES therapy would result in hypertrophy of gluteal and hamstring muscles, and an increase in LL-LBM, total LBM…
Part 1:To determine the effect of depth of anaesthesia, as quantified by pEEG, on the quality of Tc-MEP measurements during spinal surgery.Hypothesis: lower depth of anaesthesia, defined by higher values of pEEG will:a. Decrease the threshold…
The purpose of this post-approval protocol amendment is to extend the follow-up of subjects who were originally enrolled in theRCT, EUBARD-CP_001 protocol. This study extension will examine the long-term survivorship of the Barricaid® ACD when…
Co-primary objectives:Hemorrhagic complicationsPerioperative blood lossPerioperative blood loss is determined by measuring blood recovered in the suction device during surgery and weighting of blood saturated gauzes used during surgery. In case a…
This project focuses on the characterization of the immune response following a traumatic SCI. As individual components of the immune response work in close collaboration and have a strong influence on each other, it is important to obtain a very…
Objective: The primary objective of this proposal is to develop new sensitive and quantitative outcome measures for clinical trials in LBSL. The secondary objective is to identify biomarkers to stratify patients based on disease progression rate.
Objective: To demonstrate that smoking cessation in the postoperative period has a positive impact on the clinical and radiological outcomes of instrumented spine surgery
The aim of this research proposal is to examine the effect of different ISIs on mTc-MEPs.Primary research question: What is the effect of different interstimulus intervals (ISIs) on mTc-MEP thresholds, peak-to-peak amplitudes, and area under the…
To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective than only usual in individuals with chronic SCI who often have PU*s and/or are at high of recurring PU*s regarding: 1)…
Primary objective:Does the use of the application support a positive lifestyle development?Secondary objectives:Does the use of the application support an increase in physical activity levels?Does the use of the application has a positive influence…
To obtain comprehension in the development of quality of life during and after clinical rehabilitation and the factors that influence it. This leads to the following questions:Primary questions(1) What is the progress of mental health and well-being…