41 results
To determine if a marked change in the concentrations of one or more of the selected biomarker is evident before PUs are visible
The main objective is to investigate if the sensation of children with an upper OBPL is diminished. Both children that were treated conservatively as children that were surgically treated with nerve surgery in early infancy.The primary research…
Primary Objective: Evaluate the functional integrity of the nociceptive system after percutaneous cervical chordotomy using Laser Evoked Potentials Secondary Objective(s): change in opioid consumption after percutaneous cervical chordotomy using a…
Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…
1) To study the prevalence of secondary health conditions in persons with long-term SCI. It is hypothesized that longer duration of injury is associated with a higher prevalence of secondary health conditions.2) To explore the impact of secondary…
The purpose of the this study is to evaluate the prognostic capabilities of biomarkers in CSF in patients with SCI.
Aim of the study is to evaluate if the optical tissue stylet technology can discriminate tissues that are relevant to recognize for interventional pain procedures.
The primary objective of this study is to investigate the potential of the photonic needle to discriminate between correct and incorrect placement of the needle tip in the target area of the procedure (M4 - tissue), as confirmed by contrast-enhanced…
Investigating the relationship between post traumatic stress disorder, psychological factors and pain in Spinal Cord Injured patients.
The primary objective is to find out whether there is enhanced processing of sensory stimuli when people are in pain and to find out whether SCS has influence on the processing of sensory stimuli applied on non painful body parts. We focus on the…
Gain insight in the anatomy and organisation of the sacral plexus in children with NB and congenital spinal or sacral anomalies. Possible findings can be compared with the results of the healthy subjects, in order to be able to relate findings to…
Our main aim is to describe the 24-h circadian rhythm of skin and core body temperature in people with SCI and examine whether changes in melatonin and/or cortisol relate to the altered circadian rhythm in core body temperature recently described in…
The goal of this pilot study is to collect data about basal values and variations in these values of the damage markers FABP, Myoglobin, CK and CRP of people with a low complete spinal cord injury. This pilot study is a preparation for a large…
The purpose of this study is to determine if the development of idiopathic scoliosis is related to neuropathic detrusor/sphincter dyssynergia. When bladder and sphincter function are disturbed, adequate therapy can be started in an early phase to…
Reserach to the observation of neurophysiologic pain mechanisms and the differences between healthy subjects and pain patients.
1. What proportion of X-ALD carriers have symptoms en what are those symptoms (as evaluated by history, neurologic examination and electrophysiology)?2. At what age did symptoms fist manifest themselves and how is the progression of those symtpoms?3…
The purpose of the this study is to evaluate the prognostic capabilities of DWI and biomarkers in CSF in patients with SCI.
The aim of this research is to examine the effects of changes in proprioceptive and visual information on balance control in WAD sufferers. Although clinical experience suggests more effective balance control due to elevated proprioceptive…
To collect data regarding the prevalence of:I) - osteoporosis in SCI patients and the relation to characteristics of SCI. - fractures in SCI patients and the relation to characteristics of SCI. - active treatment of osteoporosis in SCI patients.II…
To visualize the affected nerve roots using DTI with tractography. The anatomy and organisation of the nerves on the level of the lumbar disc herniation will be visualized. Diffusion parameters as FA, ADC, AD, and RD could provide valuable…