35 results
Primary objective:To show that addition of dead space to low-pressure nCPAP (which is usually not effective but can be relatively well tolerated) makes the therapy effective and diminishes the apnea hypopnea index with >10/hour in patients…
The current research is set to provide insight into the phenotypic characteristics of DSPD patients in terms of psychological characteristics, occurrence of co-morbidities, and behavioural characteristics such as bedtime routines and lifestyle, and…
To investigate the incidence and severity of disturbed biorhythm among ICU patients, and the effect on quality of sleep. We also aim to validate the novel ICU Depth Of Sleep (IDOS) index in detecting depth of sleep over time. Secondarily: we will…
With this study we aim to investigate the emotional development, behavior, social behavior, variation in personality traits and intellectual functioning in a group of children who are diagnosed with narcolepsy with of without cataplexie, according…
The aim of this study is to investigate the differences between RLS and PLMS.
We aim to establish whether our judgment of *misperception* is really doing justice to the condition paradoxical insomniacs suffer from. We should keep in mind that our present definition of sleep, based on the standardized polysomnographic scoring…
The goals of the present study, therefore, are twofold:a) To estimate the incidence of dream/reality confusions in the narcoleptic population, relative to healthy controlsb) To provide a comprehensive description of the characteristics of these…
Primary:• To study the effect of rotigotine on nocturnal hypokinesiaSecondary:• To study the possibility of measuring nocturnal hypokinesia and its severity in a home setting• To correlate improvements in sleep quality by rotigotine with changes in…
Objective: In this pilot study experience will be obtained in the simultaneous use of PSG, melatonin assay, CBT-measurement and assessment in ICU patients.
Determination of SDB prevalence in patients after strokeDetermination of the relationships between SDB (in particular OSAS) and complants of fatigue and complaints of emotional and cognitive disturbances in patients who experienced a stroke.…
Is there a better way to detect REM sleep atonia than with the current visual analysis of submental muscle EMG? To which degree do muscles become atonic during REM sleep? Which muscle exhibit the largest decrease? How can this decrease best be…
The aim of this study is to examine if an increased number of awakenings in PTSD is PTSD dependent or trauma dependent. Furthermore, the purpose of the study is to examine if the nocturnal excretion of cortisol is increased.
The current study assesses activation of hippocampus and prefrontal cortex during sleep spindles in veterans with and without PTSD. Furthermore, the correlation between sleep spindles and memory consolidation will be examined.
Primary objectives:1. To determine the DLI threshold with optimal sensitivity and specificity. The DLI threshold is the DLI value above which the test is considered positive (and below which the test is considered negative). The optimal DLI…
This study aims to further clarify the pathophysiological mechanisms underlying the decreased vigilance, sleep/wake lapses, and the emotional processing leading to cataplexy.
To evaluate if an event (changes of heart frequency) related video-observation is a more efficient diagnostic procedure for parasomnias.
Is the muscle weakness during cataplexy due to pre- or postsynaptic inhibition? In other words: what happens with the H-reflex and Magnetic Evoked Potential during REM sleep and cataplexy?
1. To compare energy expenditure in detail between narcolepsy patients and healthy controls. 2. To compare insulin sensitivity between patients with narcolepsy and healthy controls.3. To establish the impact of chronic sodium oxybate treatment (3-4…
The aim of this study is to examine arousals in PTSD, and to investigate the correlation of arousals with nocturnal excretion of hormones of the HPA-axis.
The aim of this study is to seek evidence that such cyclic suppression exists. For this purpose, we will use the Hoffmann- or H-reflex, an electrically evoked reflex. By stimulating the tibial nerve in the knee, the alpha motor neuron in the spinal…