33 results
To investigate in an unselected memory clinic sample, the clinical value of 18F]FBB PET in terms of1. change in diagnosis;2. change in level of confidence of diagnosis;3. impact on patient healthcare management.
A. To gain more knowledge about the prevalence of TBI in male prisoners in the PPC and the relationship of TBI with violent crime and aggression. We expect that TBI is more common in violent offenders than in non-violent offenders. More specific, we…
The primary objectives are defined according to a hierarchical design: i) to tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in DM2 and MetS; ii) to investigate which cerebral…
Addictive disorders affect a steady proportion of the population, and result in significant negative personal consequences(e.g. loss of jobs, psychosocial problems) and costs to society (absence from work due to hangover, treatment costs).GHB is…
The current study will focus on the effects of an intensive programme of exposure of prism adaptation (i.e. daily exposure during two weeks) and compare these to sham adaptation.
The most important objective of this study is the validation of various examination procedure to assess fitness to drive in older persons with cognitive impairments. The assessment procedure comprises nosological dementia diagnoses (e.g. AD, FTD) ,…
The main goal of the study is to develop and validate a device that provides an objective measure of degradation of motor performance in elderly people. The device will assist to diagnose neurodegenerative disorders in the elderly at an early stage…
The primary aim is to investigate the effects of attentional focus manipulation on the performance of a repetitive leg movement task under single and dual-task conditions in ABI patients. Furthermore, it will be investigated to what extent the…
With this research we intend to fill the gap described in the previous chapter by:1) Detecting functional network changes in several causes of early-onset dementia and to characterize the specific changes for each dementia cause.2) Relating specific…
Primary objective: The ultimate goal is to achieve a more sensitive method for detecting malformations of cortical development. This encompasses two steps: the development of the method and the assessment of the sensitivity and specificity of the…
The objective of the study is to investigate the effects of bright light combined with physical activity during the morning on subjective and objective outcomes related to sleep-wake cycle and the rest-activity rhythm in persons with MCI, aged 65…
The purpose of this study is the expansion of the conventional MRI sequences for the diagnosis for patients with probable dementia. The focus is on structural imaging, anatomical and functional connectivity. Patterns of change in brain connectivity…
The purpose of this research line is to assess whether measures acquired with advanced MR neuroimaging can be used as neuropathological markers for the early diagnosis of dementia and differentiation between AD and FTD. For each project, the…
Addictive disorders affect a steady proportion of the population, and result in significant negative personal consequences (e.g. loss of jobs, psychosocial problems) and costs to society (absence from work due to hangover, treatment costs). GHB is…
to measure neural activity of the central nervous system in tinnitus related brain areas in cochlear implant recipients with chronic tinnitus and to determine the relation between this neural activity and the subjective tinnitus experience of…
To examine whether it is possible to combine the sensitivity of neuropsychological tasks with the efficiency of brief cognitive instruments.
To investigate the effect of late onset depression and inflammation on the pathological progression from MCI to Alzheimer*s disease by determining the correlation of microglia cell activation, β-amyloid deposition, brain volume, peripheral…
To improve the behavioural (neuropsychological) methods for the early diagnosis of Alzheimer*s disease (AD) and other dementias.
This project has been defined to investigate the effect of therapeutic horse riding on balance, spasticity and general wellbeing in 30 adults in the age of 18-80 with physical impairments following a stroke or non-congenital brain injury.
The primary objective of this study is to objectivate neural hyperactivity at the cortical level of chronic tinnitus sufferers compared to control subjects with the use of FDG-PET-scans.