704 results
Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…
This study aims to evaluate A-mode ultrasound for assessing JVPW characteristics as a non-invasive tool to discriminate between healthy subjects and those with pulmonary arterial hypertension patients, and to assess if JVPW changes relate to changes…
The aim of this study is to better understand the relation between cognition, sensory functions and motor control for speech in older age. Thereby, we strive for improved speech-based discrimination of typical aging from neurodegenerative declines.
Our overall aim is to develop mid-field MRI systems for low-threshold, extramural service to GP practices that can contribute to making healthcare more sustainable. In this study we want to perform the first steps towards this general aim. On one…
The primary objective of the study is to investigate the medium to long term effects of replacing the conventional CXR exam with an ultra-low-dose CT in terms of patient health.Secondary outcomes are measures are • Quantity and type of follow-up…
The primary objective is to evaluate the supporting mechanism of the pelvic floor for a Gellhorn pessary in patients with pelvic organ prolapse immediately after insertion and one week after insertion of the Gellhorn pessary.Secondary Objectives: •…
The primary objective of this study is to evaluate the clinical performance of the [Redacted] PD-L1 [Redacted] CDx Assay in terms of its ability to identify patients with non-squamous metastatic NSCLC (mNSCLC) who may benefit from treatment with […
The primary objective of this pilot study is to determine the clinical value of ocular MRI for patients with the following ocular conditions:- Glaucoma treated with a Baerveldt implant- Visual field loss- Diplopia
Primary objectives: (1) develop valid measurements using multiple methods (self-report (i.e., QUITSO), Indirect measures) to identify ITs in child molesters, pedophiles and rapists and to examine the differences between child molesters, pedophiles,…
The primary objective of this project is the development of an VR agression assessment (VRAA) with a high ecological validity, existing of VR scenario's. Furthermore the psychometrical characteristics will be explored.
Primary Objective: To investigate the feasibility, applicability, and reproducibility of a novel hyperspectral camera system in perfusion and oxygenation detection in healthy volunteers.Secondary Objectives: - To explore the effect of occlusion-…
The major objective of this study is to investigate the level and response in cortisol before and after a stressfull situations in different groups of care-givers. It is hypothesized that the best trained group will show the lowest increase in…
Primary objective: - To measure infraslow EEG changes during stress response in healthy subjects.Secondary objective(s):- To investigate if cortisol levels relate to ISA.- To explore ISA activity as a potential biomarker for stress.- To formulate…
To describe serial changes in diastolic and systolic myocardial performance by comprehensive echocardiographic assessment in neonates prior to, during, and after ECMO treatment and relate this to the course of PPHN.
To assess the feasibility of using the U-SNIFF in various European countries (e.g. the Netherlands). To validate the developed odor identification test for children (U-SNIFF), in various European countries. (e.g. the Netherlands). To assess the test…
This study aims to provide normative values for sEMG swallow function. Clinicians using sEMG for clinical and research purposes may use this data for a more complete understanding and interpretation of their results. Individual results and changes…
Primary Objective: To further characterize, develop and validate assays for candidate protein biomarkers for the diagnosis of CAA.Secondary Objective(s): To correlate the novel neurochemical biomarkers with each other and with measures of cognitive…
The primary objective is to explore the validity and reliability of the QScale during pain sensitivity measurements in pain-free subjects.
Primary Objective: Our overall aim is to improve selection of patients for epilepsy surgery and predict surgical candidacy with use of genetic test results as a biomarker. The specific objectivesare:Cohort I1. Apply genetic testing for epilepsy gene…
1). Develop a model in which the electrical activity of the diaphragm (EAdi) is used to predict the transdiaphragmatic pressure (Pdi) 2) Assess to which degree this model is accurate in estimation Pdi-derived parameters (such as work of breathing…