5297 results
1.1 Primary ObjectiveTo test the validity and reliability of two new VR emotion recognition tasks in people with psychotic disorder. This will be done by comparing the tasks to classical tests and to compare data of people with a psychotic disorder…
A number of anti-HER2 therapies have proven efficacy, are approved and part of the Standard of Care for HER2-positive BC and GC. In contrary, there is currently no clinical data on the potential therapeutic effect of trastuzumab emtansine treatment…
The primary objective of the present study is to investigate the effect of palmitic acid versus stearic acid on HDL metabolism during the fasted state. Secondary objectives are to investigate the effects of palmitic acid versus stearic acid on the…
The primary objective of the study is to investigate the effectiveness of the adapted eHeadspace Generation Next (GN) website in the Netherlands. Secondary objectives are to investigate the utility of a smartwatch for prognosis and the development…
1. To evaluate the safety and tolerability of ascending multiple oral doses of HTL18318 in healthy adult male and female subjects.2. To evaluate the pharmacokinetics of ascending multiple oral doses of HTL18318 in healthy adult male and female…
The objective of the study is to investigate how quickly and to what extent balovaptan is absorbed and eliminated from the body (pharmacokinetics) when it is administered in combination with rifampicin. It will also be investigated to what extent…
The primary objective is to evaluate the effect of the PalliSupport care pathway on the likelihood of unplanned hospital readmission, deaths at place of preference, quality of life, symptom burden and informal caregiver burden.
The objective of the current study is to validate computational models that predict neuronal activation during TMS.
This research project examines whether there are differences in effects between application of ImRs preceeded by CR and ImRs as a stand-alone treatment technique on the so-called encapsulated beliefs, cognitive beliefs based on the aversive…
First objectives To assess the influence of apical periodontitis on the peripheral blood-plasma concentration of inflammatory mediators and to investigate the metagenome of root canal infections. Other objectives: To search for clusters and patterns…
The primary aim of the study is to generate a cohort, which provides information on sex- and gender differences in: prevalence and incidence of (clinically relevant clusters of) PFS, risk factors and prognostic factors for PFS, factors that reveal…
The objective of this study is to prospectively document the performance of a fully covered self expanding metal stents (FCSEMS) for treatment of pancreatic duct strictures in patients with painful chronic pancreatitis.
This study aims to determine the digestibility of AAs in two protein sources in men and women with normally functioning ileostomies.
The study objective is to assess whether negative and positive outcome expectations, induced by verbal suggestions under both open- and closed-label conditions, can influence itch during a short-term validated histamine test. Additionally, we…
Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…
(1) Longitudinally describe the language and speech development in preterm children at 9 years of age. (2) Investigate whether these outcomes are related to a divergent development of neurological (language) system and (3) whether these language and…
The purpose of this study is to investigate how safe the new compound BAY 1213790 is and how well it is tolerated when it is administered as an injection under the skin to healthy male volunteers. BAY 1213790 has been administered to humans before.…
Primary; to determine vaccine- and non-vaccine serotype-specific pneumococcal carriage by culture. Secondary; to determine pneumococcal presence, density and multi-serotype carriage analysis using molecular methods, impact of PCV on presence of…
Objectives: To investigate the effect of a daily sachet of probiotics on vitamin K status for 12 weeks vs placebo.
To develop, optimize and evaluate MRI sequences and technology.