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To evaluate the efficacy of low molecular weight heparin (LMWH) in women with inherited thrombophilia and recurrent miscarriage on live birth.
We seek to elucidate the perinatal exposures to DEHP and BPA with the intention of providing evidence for policy makers and manufacturers. It is our hope that less toxic products will be used in health care and in the general population in the…
First ObjectiveIn this study we compare a policy of labour induction at 41 weeks with a policy of expectant management until 42 weeks, with an outpatient check for CTG monitoring and ultrasound measurement in the 42nd week, with respect to the…
The aim of this study is to investigate the effect of guided tapering in early pregnancy as compared to continuation of SSRIs during pregnancy. We will study effects on both mother and child with a pragmatic approach.
To investigate the effect of maternal hyperoxygenation with 100% in the second stage of labor and in the presence of abnormal fetal heart rate (FHR) patterns on fetal condition, instrumental delivery rate and free radical production. In case a…
The APOSTEL-VI study will assess whether a cervical pessary prolongs pregnancy in women who have been admitted for threatened preterm labor with a positive fibronectin test, but remained undelivered. Furthermore we will study whether a cervical…
To assess whether a higher prophylactic platelet transfusion threshold is superior to the lower thresholds in reducing the proportion of patients who experience a major bleed or death up to study day 28.
The primary objective of the SafeBoosC trial is to examine if it is possible to stabilise the cerebral oxygenation of extremely preterm infants (gestational age < 28 wks) during the first 72 hours of life through the application of cerebral…
The striking difference in uptake of Down*s Syndrome screening between countries that otherwise show close resemblance, particularly regarding healthcare policy, social and cultural factors (including non-directiveness of counselling, autonomous and…
Disease activity, perianal involvement and lesion localisation are important influential parameters making sure no pregnancy is exactly alike and mode of delivery needs to be considered on an individual patient level.A complete anorectal function…
Primary objectives:To determine the difference in effect of prophylactic daily LMWH injections with standard high risk antenatal care compared to standard high risk antenatal care only for the prevention of preeclampsia and IUGR and to assess the…
The goal of this study is to develop and test two tailored intervention programs to stimulate pregnant women to stop drinking alcohol. These intervention programs are a health counseling and a computer tailored intervention. The efficacy of the…
For pregnant women with non-severe non-proteinuric maternal hypertension at 14-33 weeks, will *less tight* control (target dBP of 100mmHg) vs. *tight* control (target dBP of 85mmHg) increase or decrease the likelihood of pregnancy loss or neonatal…
a. To study whether a specific set of biomarkers is associated with PE with DVb. To study whether a specific set of biomarkers is predictive of PE with DV.
Storage of blood samples, placental material and ultrasonic measurements to be used in a future study the prediction of PE and DV.
This study will answer the question if (repeated) abdominal amnioninfusion after midtrimester PPROM with associated oligohydramnios improves perinatal survival and prevents pulmonary hypoplasia and other neonatal morbidities. Moreover, it will…
The overall aim of the DALI study is to identify the best available measures to prevent GDM in an ongoing pregnancy, to provide a cost-benefit calculation of GDM prevention for health care systems, and to establish a pan-European cohort of mother-…
This study will answer the question whether surgical intervention (metroplasty) in women with recurrent miscarriage and/or subfertility and a septate uterus will improve their reproductive outcome.
Fertility follow-up of the women who visited our out patient ward for information on fertility preservation before starting gonadotoxic treatment
1) To test the feasibility of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in newborn babies.2) To test the safety of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in…