111 results
The main question in the study isHow do moderately preterm infants and their parents differ from term, as well as extreme preterm infants in (a) development and self regulation skills of the infants, (b) interaction patterns and relationship between…
Objective #1: Implement clinical platform. We see the need to implement a clinical platform for two purposes. First, we want to design a biomarker profile of perinatal brain damage in human newborns (see above). Thus, we have established a…
1- To determine the physiological concentrations of ADAM12 and PP13, longitudinal, in the early first trimester in normal pregnancies. 2- To analyse the stability of these proteins, the effect of transport and higher temperatures.3- To compare the…
Primary Objectives: To prospectively investigate the changes in cardiac parameters (echocardiography, NT-pro-BNP) and uteroplacental flow (pulsatility index, diastolic notching) during/after pregnancy in women with CHD and compare these changes with…
1. To identify associations or an absence of associations between complaints and impaired daily functioning.2. To get an insight in events in pregnancy related to persistant complaints and impairments in daily functioning after pregnancy.
This study is focused on determination of risk factors associated with preeclampsia and intrauterine growth restriction, both develop in early pregnancy. These pregnancy complications are associated with cardiovascular diseases in later life. We…
The objective of this study is to examine the consequences of the use of an SSRI in pregnancy for motor and cognitive development of the child, in the short and long term.
To compare insulin sensitivity in full term neonates and preterm neonates at term, and to compare insulin sensitivity in small and appropriate for gestational age infants.
To determine and compare the periodontal status between the different groups of women. Periodontal examinations will be performed within one week after delivery. If periodontal disease is diagnosed within the selected groups, it is plausible to…
To prove that 1 corticosteroids administration is the main factor in diminished bone density of preterm neonates, 2 dexamethasone has more influence than hydrocortisone and 3 children with abberant ricketsscreening have a transient diminished bone…
to determine the correlation of fetal hyperinsulinemia (measured by urine c-peptide) and maternal indicators of glucose-regulation with neonatal birth weight and postpartum glucose concentration of macrosomic infants of non-diabetic mothers
Aim of this study is to identify how pregnancy complications can be predicted from the interplay between psychological, social and somatic risk factors. We hypothesize that the personality trait neuroticism predisposes to complications of pregnancy…
In this pilot study we intend to measure Tregs in umbilical cord blood, in normal as well as in pregnancies complicated by preeclampsia, and will define their use as a predictor of the risk for developing allergic diseases in the child.
An explanation of the complete spectrum of anomalies seen in fetuses with increased NT could be a disturbed endothelial differentiation related to the cardiovascular development. Cardiac defects form the severe end of the spectrum. More data, both…
To quantify splanchnic and whole body aspartate metabolism in premature neonates.
The objective of this study is to evaluate a new and less invasive method of PGS. The new PGS technique will analyse a nucleus of a blastomere that was obtained by nuclear extraction rather than by biopsy of a whole blastomere.
1. To determine the rate of splanchnic utilization of glutamine, proposed to be conditionally essential for premature infants.2. To quantify the rate of splanchnic oxidation of dietary glutamine, which is supposed to be one of the major fuel…
To determine the cardiovascular changes in response to orthostatic stress in women with a vascular complicated obstetric history or recurrent miscarriage.
To determine the best method of measuring venous compliance in women.To determine the influence of orthostatic stress on venous compliance and the best method to measure VC during orthostatic stress.
The objective of this study is to test the hypothesis that healthy obese pregnant women at increased risk for obesity-related pregnancy complications can be identified by a subgroup-specific screening program at twelve weeks amenorrhea.