36 results
The next questions will be addressed in the present study: 1. Do moderately preterm infants differ in development and attention and concentration capacities from a term and very preterm infants during the first years of life? 2. Do attention and…
The aim of the current study is to get insight into the in potential lifelong consequences of active disease and or prednisone use during pregnancy on the children of women with rheumatoid arthritis. As readout it uses indicators (risk factors) for…
1. To describe the development of the nature of the immune system in early life in a profile of cytokines, chemokines and adipokines. 2. To evaluate less invasive methods like the use of saliva or less demanding methods like the use of dried bloods…
The project aims to gain more insight in the process of bonding between parents and prenature infants, to validate a screening instrument that can be easily adopted in maternity wards of (general) hospitals to detect parents and children at risk for…
The main question in the study isHow do moderately preterm infants and their parents differ from term, as well as extreme preterm infants in (a) development and self regulation skills of the infants, (b) interaction patterns and relationship between…
Objective #1: Implement clinical platform. We see the need to implement a clinical platform for two purposes. First, we want to design a biomarker profile of perinatal brain damage in human newborns (see above). Thus, we have established a…
To evaluate the predictive value of microcirculatory perfusion for the incidence of Extracorporeal Membrane Oxygenation (ECMO) dependency and consequently survival. To evaluate the effects of vasopressor drugs and iNO on microcirculatory perfusion.
To establish microcirculatory profiles using non-invasive diagnostic imaging in NEC.
The main objective of the study is to provide insight in the developmental problems of very premature and/or VLBW children compared to their term born peers, and to investigate the possible beneficial longitudinal effects of the GEEF intervention on…
The objective of this study is to examine the consequences of the use of an SSRI in pregnancy for motor and cognitive development of the child, in the short and long term.
- To analyze retinoid levels in plasma and amniotic fluid from infants and mothers to establish the potential link between retinoids and CDH. - To establish a registry of blood and tissue samples that will be valuable for future studies of the…
In this pilot study we intend to measure Tregs in umbilical cord blood, in normal as well as in pregnancies complicated by preeclampsia, and will define their use as a predictor of the risk for developing allergic diseases in the child.
The objective of this study is to describe the association of physical, neuromotor, neurocognitive and social-emotional development with the parent-child interaction in high-risk NICU graduates at the age of 5 years, compared to term born age mates…
To prove that 1 corticosteroids administration is the main factor in diminished bone density of preterm neonates, 2 dexamethasone has more influence than hydrocortisone and 3 children with abberant ricketsscreening have a transient diminished bone…
To compare insulin sensitivity in full term neonates and preterm neonates at term, and to compare insulin sensitivity in small and appropriate for gestational age infants.
The main objective of the study is to construct reference curves for fetal bladder diameters and volume in the second and third trimester of pregnancy. Moreover we will investigate the variation in the dimensions of renal pelvis in relation to the…
Primarily, to study the relation between neonatal cerebral oxygen saturation and extraction and intelligence at 4 years of age in infants born following intrauterine growth restriction. The second aim is to study the relation between neonatal…
The primary objective of the study is to examine muscle atrophy in fetuses with single or bilateral IPEV, in comparison to a normal population by measuring the circumference of the upper and lower legs by ultrasound examination. The length of the…
The quality and quantity of the innate immune response to bacteria should be tightly regulated leading to resolution of infection while minimizing damage to host tissue. We hypothesize that this regulation depends on gestational age at delivery and…
The objective of the study is to identify biomarkers that associate to brain (physiological) status or mental (functional) health status and their interaction. More specific, our first aim is to determine the association between neuroinflammatory…