149 results
To obtain a fundamental understanding if and which chemotherapeutic agents used for treating cancer during pregnancy are associated with offspring (epi)genetic changes, potentially causing FGR and childhood/adult diseases later in life.
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using 2-D, 3-D, pulsed wave Doppler, Tissue Doppler and (blood) speckle tracking (focussing on strain and strain rate) between fetuses/neonates with structural heart…
Our main objective is to explore the relationship between nutritional intake, growth, body composition and brain development. Hereby we want to improve our knowledge about how to feed the preterm infant in a way that contributes to a better…
Primary ObjectiveIn order to assess the effects of anti TNFα on the development of adaptive and innate immunity, children exposed to anti TNFα (with or without other immunosuppressive drugs) will be compared to children exposed to immunosuppressive…
The primary aim of this study is to investigate the safety and feasibility of ultra-high field magnetic resonance imaging (MRI) of the brain in neonates and to optimize scan protocols.
1.To explore the intrauterine cerebral development by ultrasound in healthy fetuses to compare to the findings in fetuses with severe CHD. We want to do this by establishing benchmark values in healthy control fetuses, to compare these with our…
To assess the effectiveness of low dose aspirin compared with placebo in prevention of recurrent spontaneous preterm birth.
Our primary objectives are: 1. To evaluate the effect of Family Integrated Care in SFR on neurodevelopmental outcome at 2 years of (corrected) age in newborns hospitalized in a level-2 Neonatal Ward for at least 1 week as compared to standard…
To evaluate whether cervical pessary can replace cervical cerclage in women with previous preterm birth and a short cervix or in women with a history of multiple preterm births in terms of effectiveness and costs
To study cognitive and behavioral outcome and resting-state dynamics in children with a history of perinatal asphyxia before and after the introduction of hyothermia and to compare these data with a group of controls.
To determine whether blastocyst stage embryo transfers improve the cumulative live birth rate compared with cleavage stageembryo transfers in IVF/ICSI treatments
To determine the feasibility of measuring SpO2 and HR by applying a pulse oximetry probe to the umbilical cord at birth in term neonates undergoing PBCC.
Our first aim is to study whether it is feasible to provide live-music therapy for extremely preterm infants. Our second aim is to evaluate possible effects of live-music-therapy, to serve as a basis for power calculations in a larger study. This…
The primary objective of this study is to investigate the effects of stress exposure on the epigenetic profile of preterm infants. Secondary objectives include to determine (a) the relation between stress exposure and early childhood outcomes (…
To determine the accuracy of the *NeoBeat* device against gold standard measurements obtained by an ECG monitor with disposable (gel) electrodes and against pulse measured preductally as derived by pulse-oximeter.
Primary objective: to determine the association between social and cognitive performance of preterm-born young adults and their early motor repertoire up to 3 months after term. Secondary objective: to describe the social and cognitive functioning…
To evaluate detection thresholds, functioning of the HPA-axis and risk of chronic pain in children of 5-years of age who experienced pain and received morphine in neonatal period in compare with children of 5-years of age who experienced pain…
The primary objective of the study is to assess the proportion of neonates with hyperbilirubinaemia necessitating treatment that is detected using universal TcB screening compared to using only visual inspection, while decreasing the number of heel…
To describe serial changes in diastolic and systolic myocardial performance by comprehensive echocardiographic assessment in neonates prior to, during, and after ECMO treatment and relate this to the course of PPHN.
In this research study we observe the effect of breathing on placenta- to infant transfusion, by measuring bloodflow in the umbilical vein, vena cava inferior, ductus venosus and hepathic vein, to get a better understanding of the underlying…