Search for a trial

Comparison of Point-Of-Care Testing and venous blood glucose samples at the oral glucose tolerance test in pregnancy: a prospective observational cohort study

To assess the utility and diagnostic accuracy of capillary glucose samples (using the Roche Accu-Chek Inform II point-of-care testing device) compared with venous glucose samples with laboratory determination as the gold standard. To determine the…

Screening gestational diabetes: glucose curve versus oral glucose tolerance test

The primary objective is to compare the glucose curve with the OGTT, as a screening test for GDM.The secondary objective is to see if GDM treated after screening either with the glucose curve or with the OGTT, can predict perinatal complications and…

PREGCOVAC-19: the follow up of pregnant women who received COVID-19 vaccination in the Dutch national vaccination program

We have defined the following milestones/deliverables for this project:1. Evaluation of IgG antibody response in pregnant women after participation in the Dutch national COVID-19 vaccination program.2. Evaluation of the relation between gestational…

The efficacy of intermittent versus daily oral iron supplementation in anaemic pregnant women.

To compare the efficacy, side effects and therapy compliance of intermittent (three times a week) versus daily oral iron supplementation for anaemia in pregnancy attributed to iron deficiency.

Diagnostic value of saline infused sonography compared to hysteroscopy in detecting retained products of conception.

The main objective is to compare the test characteristics (sensitivity, specificity, positive and negative predictive value) of SIS with hysteroscopy for the diagnosis of RPOC. Secondary objectives are the complications related to the diagnostic…

A randomised controlled trial investigating the effect of virtual reality on labour analgesia use

The aim of this study is to investigate whether VR will decrease the request for labour analgesia. Primary outcome measure:* Request for labour analgesiaSecondary outcome measures:* Patient tolerability, feasibility and satisfaction of VR use (VR-…

Inter- and intra-observer variability in first-trimester uterine artery Doppler measurements.

To assess the inter- and intra-variabiltiy of the Uterine Artery Doppler measurement in first trimester pregnancies.

Pharmacokinetics of tacrolimus during pregnancy in kidney and liver transplant recipients.

The overall aim of the study is to gain more insight in as well as understand and map the pharmacokinetics of tacrolimus during pregnancy. Therefore, we will study tacrolimus concentrations in maternal whole blood (routine care) and via area under…

closed-loop insulin delivery in pregnant women with type 1 diabetes: a randomized controlled trial

this research answers the need to evaluate whether the 780G hybrid closed-loop system in pregnant women with T1DM can improve glycaemic control with less hypoglycaemia. This in turn, might improve pregnancy outcomes in women with T1DM.