112 results
The purpose of this pivotal study is to demonstrate long-term safety and efficacy of hypoglossal nerve stimulation to treat obstructive sleep apnea (OSA) using the Inspire II system and to support market release in the United States, Europe and…
Investigation of the prevalence of sinonasal disease on CT-sinus in children with Cystic Fibrosis at different ages. This study will focus especially on the onset of sinonasal pathology in Cystic Fibrosis in relation to the development of the…
This study is designed to evaluate the safety and performance of SinuBand, a bioresorbablefluticasone propionate-eluting sinus dressing in the postoperative management of FESS in patientswith chronic rhinosinusitis. The study will collect both…
The Purpose of the study is to investigate the clinical feasibility of the TW15 and TW22.
Primary Objective: Can an e-Health application, based on objective measurements, maintain the daily physical activity of COPD patients after a period of rehabilitation?Secondary Objective(s): • Are COPD patients motivated to use the e-Health…
Feasibility study of the option NAVA (Neurally adjusted ventilatory assist) on the Servo-i in ventilated children in the age of 0-18 on the PICU and the NICU of the Erasmus MC -Sophia Childrens hospital in Rotterdam.
Primary objectives:1. To analyze the exact pathogenic mutations in the TCOF1 gene in TCS 2. To determine the severity, prevalence, natural course within the cohort TCS patients and potential metabolic and physical effects of OSAS in TCSSecondary…
To demonstrate superiority of tiotropium vs. salmeterol in reducing exacerbations which are an important patient outcome because they are a major cause of morbidity from COPD. In addition, they are associated with a more rapid decline in lung…
In The Netherlands 2% of women and 4% of men suffer from Obstructive Sleep Apnea Syndrome (OSAS). NCPAP, the gold standard therapy for moderate to severe OSAS has been shown to reduce blood pressure in OSAS. NCPAP therapy is however hampered by…
The aim of this study is to investigate if bidirectional delivery, by delivering more drug to the region of the sinus ostia, improves upon the efficacy of current nasal steroids in chronic rhinosinusitis.to get information about the efficacy, safety…
the primary objective of this study is to investigate whether a structured program including exercise training and dietary advice is feasible in mild OSAS patients in a primary care setting.
The primary objective is to evaluate the percentage of the study population who have OSAS before and after treatment and the severity of it. A second objective is to correlate the prevalence of OSAS with different tumour sites and stages, as well as…
To assess the normal nasal microcirculation in vivo. Also, this research may lead to a better understanding of the pathophysological mechanisms operative in nasal dysfunction. It may help us to differentiate between aetiology of different disorders…
By a chemical, physiological and IgE-mediated nasal provocation test, nasal responses will be provoked in different patientgroups. The clinical response will be measured by visual analogue score, rhinitis symptomscore, peak nasal inspiratory…
to study postoperative oxygenation patterns in patients with OSA during the first three postoperative nights and 6 weeks after operation. The results of these observations will be compared to other patients groups with known respiratory compromise…
Can inertial sensors be used to detect upper airwayobstruction?
* To study systemic inflammation in individuals who are or are not susceptible to develop COPD. * To characterize the switch to chronicity of the systemic inflmmatory response in COPD* To determine whether the type and severity of the systemic…
Evaluation of the three-dimensional airway with a Conebeam CT(CBCT) scan to evaluate the upper-airway's in patientis with different degrees of severity of OSAS.
Analyze the correlation between change in EELV with change in MIF50
To assess 1. the burden of allergic disease across Europe*s aging population2. the association of severe asthma with potential risk factors and their impact on lung function decline over time3. the association of asthma severity with sex hormone…