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Electrode positioning of transcutaneous electromyography of the diaphragm in preterm infants

To identify alternative dEMG electrode positions in preterm infants for cardio-respiratory monitoring.

Monitoring lung fluid clearance and aeration during pulmonary transition after birth

The objective of this study is to obtain physiological data on lung aeration during pulmonary transition in newborn infants.

Titrating to the optimal pressure. Is transcutaneous electromyography of the diaphragm a good measurement to determine the optimal respiratory support, during continuous positive airway pressure (CPAP), in pre-term born neonates.

Primary question:Are dEMG measurements a clinical marker to assess the WOB in preterm born neonates?

The effect of breathing on placental venous return in infants at birth: an observational study

In this research study we observe the effect of breathing on placenta- to infant transfusion, by measuring bloodflow in the umbilical vein, vena cava inferior, ductus venosus and hepathic vein, to get a better understanding of the underlying…

Phase Ib, multicenter, open label study of PDR001 in combination with platinum-doublet chemotherapy in PD-L1 unselected, metastatic NSCLC patients

Primary: Dose confirmation part: To establish the Maximum Tolerated Dose (MTD) and/or Recommended dose for expansion (RDE) of PDR001 with platinum-doublet chemotherapy in treatment naïve patients with PD-L1 unselected, advanced NSCLC of squamous or…

Electrical activity of the diaphragm as predictor of detubation failiure

To determine the impact of detubation on changes in electrical activity of the diaphragm in adults, children and neonates.