52 results
The primary objective is to study the level and time course of the end-expiratory lung volume during the individual incremental * decremental PEEP titration; the secondary objective is to study if there is a significant association between the end-…
The primary objective for this study is to compare the level and time course of the patient work-of-breathing during PS ventilation with the work-of-breathing during SIMV-PS ventilation with a lower rate of breaths per minute delivered by the…
The purpose of this research project is to improve the overall quality and resolution of the MRI images, to correct for movement effects during the procedure and to speed up the investigation. The goal is to enhance and standardize a technique…
The primary objective is to assess the association between the EELV measured with RIP and EIT, and to graphically depict the changes in the pressure volume curve during stepwise decreasing the CDP in a recruited lung and correlate these with…
To determine the true prevalence of pneumonia in exacerbating COPD patients by low-dose CT
To study the effects of varying amounts of air and patient position on oesophageal pressure measurements in children with and without lung injury.
The purpose of this study is to compare the Metronome-Paced Hyperventilationtest (MPH) with cardiopulmonary exercise testing (CPET) in patients with COPD for detecting dynamic hyperinflation, thereby establishing the diagnostic accuracy for dynamic…
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
We hypothesize that an electronic nose can discriminate between the exhaled breath of patients with established pulmonary sarcoidosis from healthy controls Secondly, we hypothesize that an electronic nose can discriminate between different stages of…
The primary objective is to establish the point prevalence of Airflow Limitation (AL) compatible with COPD, in current/former smokers, with established cardiac diseases, in Europe. Secondary Objectives are: • To establish the point prevalence of AL…
Primary Objective: Which physiological impairments and complaints are present during activities of daily living in patients with mild COPD? Secondary Objective(s): Are physiological impairments and complaints during activities of daily living…
Information on feasibility of spirometry, impulse oscillometry and body plethysmography in adults with mild and moderate intellectual disabilities.
Primary Objective: To determine whether or not our newly developed MRA with accelerometer can measure the therapy-effect of the MRA by determining the correlation of the treatment-efficacy of an MRA measured by an integrated accelerometer built in…
First Objective: Is the percentage of subjects that dynamic hyperinflate during activities of daily living larger in patients with mild COPD than in healthy controls?Second Objective(s): Will dynamic hyperinflation induced by activities of daily…
The primary objective is to asses the association between the EELV measured with RIP and EELV volume measured with electrical impedance tomography (EIT). Secondary objectives include a) studying the association between the EELV measured with RIP and…
To evaluate the effectiveness of the Chartis System in selecting subjects with heterogeneous emphysema who will achieve Lung Volume Reduction from Endobronchial Valve therapy.
This observational study is designed to test the hypothesis that the Bicore-IITM technology may act as a useful bedside tool during lung recruitment, as well as a tool in the differentiation between lung overdistension or a worsening of disease…
The objective of the standardized protocol is optimalizing the accuracy of the diagnosis (all-cause pneumonia, or serotype-specific pneumonia) during the 13-valent pneumococcal vaccin (13vPnC) study which will be performed in 2008. Additionaly, the…
The primary objective of this current proposal is to test validity of the MPH test to detect DH. Validity is analyzed by comparing MPH-induced DH with DH induced by a symptom-limited incremental cycle exercise test.
To assess whether the GdMRI can fit in the annual check up.To assess whether the GdMRI is sensitive to monitor and follow up on the peripheral bronchiectasis and areas of hypoperfusion. To compare the distribution and volume of hypo perfusion on…