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Diaphragm-protective mechanical ventilation in critically ill patients: A proof of concept study.

Primary objective of this study is to assess the feasibility of using a monitoring and a titration algorithm to prevent inactivity and excessive activity of the diaphragm. This will be determined by comparing the fraction of breaths where diaphragm…

Effects of high-frequency neuromuscular electrostimulation with external weights in patients with chronic obstructive pulmonary disease with severe symptoms of shortness of breath and dysfunction of lower extremity muscles: a pilot effects study.

The aim of this study is to determine whether external weights affect the intensity of NMES and the possible effects on metabolic processes and muscle activity in COPD patients.

Effect of palivizumab on respiratory syncytial virus-associated burden of disease - a randomized controlled trial

It is not known whether recurrent wheeze in preterm children is caused by RSV infection (serial hypothesis) or that RSV infection is the first indication of chronic airway morbidity that would develop anyway (parallel hypothesis). This study aims to…

Breath synchronized electrical stimulation of the abdominal wall muscles to prevent respiratory muscle atrophy during the acute stages of mechanical ventilation therapy

The primary objective of this study is to investigate whether electrical stimulation applied to the abdominal wall muscles in synchrony with exhalation can be feasible to prevent the development of atrophy of the abdominal wall muscles during the…