96 results
Ex vivo study: What is the relation between increasing heparin concentrations and different protamine:heparin-ratio*s with POC-PT values in blood drawn from healthy volunteers?Clinical study in cardiac surgery: Does the POC-PT device correspond with…
The objective is to investigate the effect of strenuous exercise (participation to the Amstel Gold Race) on coagulation and haemostatic parameters.
To investigate if ultra low-dose chest CT may be a better diagnostic tool than chest X-ray on day 1 of febrile neutropenia. Imaging results will be compared with a consensus diagnosis on the cause of febrile neutropenia made by an expert panel.…
The primary objective of this study is to establish the diagnostic accuracy of ultrasound assessment of the synovium in haemophilic arthropathy compared to MRI. Secondary objectives are (2A) to determine whether or not synovial hypertrophy on MRI is…
to analyse the applicability of neutron activation analysis in measuring the absorption of a trace dose of the stable 58 Fe isotope orally given as ironsulphate
1. Determine whether thrombo-elastography (TEG) the occurrence of postoperative blood loss and transfusions can predict after cardiac surgery.2. Determine whether platelet aggregometry (Multiplate and Verify Now) can predict the occurrence of…
(i) identification and cellular characteristics of red blood cells from patients with altered ion homeostasis and delivery of novel and easy-to-use diagnostics for rare anemia*s, for patients with: a) a known primary defect in the ion channels of…
The objective of this study is to evaluate the additional value of novel anemia markers (RET-HE, RPI, sTfR, sTfR/log(ferritin), transferrin/log(ferritin)) in a prospective, randomized study design. Our hypothesis is that the novel anemia markers can…
The main object is to evaluate the validity of a diagnostic screening package for bleeding tendency consisting of point-of-care devices when compared with the gold standard for bleeding tendency diagnosis.Other objects which will be investigated are…
The aim of this study is to determine the levels of hemostasis factors after an uncomplicated pregnancy.
The aim of this study is to investigate if there is a correlation between the clinical phenotype (defined as age of first bleeding and bleeding score) of patients with severe haemophilia A and the results of the whole clotting assessment (TM-ETP + T…
Serum hepcidin levels are elevated in hemodialysis patients and may contribute to functional iron impairment and thus to ESA-resistance. Kinetics of hepcidin in hemodialysis patients has not been studied in detail. This study is designed to provide…
to determine the immediate effects of alcohol consumption in healthy volunteers on haemostasis and to evaluate the differences of artificially alcoholised blood and *naturally*, via oral uptake alcoholised blood on haemostasis as measured by…
To study whether microcirculatory perfusion is improved by ECMO. Perfusion will be studied before & after ECMO start, during ECMO weaning and before & after ECMO stop. To study the precictive value of perfusion and its correlation…
Objective: The primary objective of this pilot study is to compare FDG-PET-CT with HR-CT alone and to HR-CT and galactomannan test together for early diagnosing IFIs in neutropenic patients.
We aim to determine whether the change in Ret- He, RBC- He and hepcidin concentration to one or two weeks iron supplementation therapy predicts the increase in hemoglobin concentration after 6 weeks of oral iron supplementation therapy in anemic…
Objective:The hypothesis of this study is that laboratory markers for blood coagulation, platelet activity and inflammation may help to identify patients at risk for a recurrent cardiovascular event after ACS. Secondary, we expect to find…
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
Objective of the study:Investigating with use of the classical coagulation tests on one hand and with the ROTEM on the other hand what is exactly becoming disturbed in the coagulaton because of bleeding during surgery of the aorta abdominalis,…
In the present ex vivo study we aim to determine whether thromboelastometry parameters, in particular the lysis onset time (LOT), are appropriate to determine and quantify the degree of hyperfibrinolysis. Furthermore, we will study the association…