23 results
The objective of this trial is to investigate whether Eltrombopag added to standard immunosuppressive treatment increases the rate of early (at three months) complete response and blood counts and can be use as front-line therapy for SAA treatment.
The objective is to investigate the effect of strenuous exercise (participation to the Amstel Gold Race) on coagulation and haemostatic parameters.
To assess the ex vivo cytokine production of whole blood during 28 days after phlebotomy (routine withdrawal of 500 ml of blood).
To get more insight into lymphocyte kinetics during immune reconstitution after hematopoietic stem cell transplantation
Objective: The primary objective of this pilot study is to compare FDG-PET-CT with HR-CT alone and to HR-CT and galactomannan test together for early diagnosing IFIs in neutropenic patients.
1. To establish whether serial exhaled breath analysis using eNose can detect invasive pulmonary aspergillosis in patients with prolonged chemotherapy induced neutropenia (neutrophil counts <0.5 x 10^9 for more than 7 days).2. To establish…
Evaluation of acute joint damage immediately after a joint bleed in patients with haemophilia, by use of a panel of state-of-the-art biomarkers of cartilage and bone turnover measured in blood and urine. The question that will be addressed is…
In this study, we will investigate the use of optical spectroscopy in determining neonatal bilirubin and hemoglobin blood levels. The outcome and accuracy of the optical spectroscopy measurements will be compared to the outcome of laboratory blood…
The aim of the project is to investigate the effects of five contrasting air pollution scenarios on respiratory and cardiovascular health of young healthy volunteers.
to establish the accuracy with which the eNose can discriminate patients with invasive pulmonary aspergillosis from controls
To demonstrate the accuracy of FLT-PET to be an early response parameter for haematological recovery.
The determination of a panel of markers associated with endothelial cell activation and/or damage in patients with a hematologic malignancy, receiving intensive treatment, or sickle cell disease in relation to the effects of transfusion intervention…
To evaluate whether acute stress induced by a byngy jump alters the status of the innate immune system
Aim of the study* To determine age-and sex-dependent reference values of the iron regulatory hormone hepcidin.* To determine age-and sex-dependent reference values of newer parameters to determine iron deficiency, such as soluble Transferrin…
- Identify hemato-oncology patients and conditions with a high versus a low bleeding risk, by epidemiological research and a short questionnaire. - Investigate the association of bleeding related biomarkers with bleeding.
Primary Objective: The main goal of this project is to identify CVR predictors including CBF, age, sex and vascular stressors in anaemic and control patients using several MRI techniques. While anaemia is correlated with other cerebrovascular risk…
We aim to validate the TSAT/hepcidin ratio as a diagnostic tool with a high specificity and to establish a cut off point in order to discriminate between Iron Refractory Iron Deficiency Anemia (IRIDA) and iron deficiency anemia (IDA) not because of…
The Biobank 'Leukemia, Myeloma, Lymphoma and Myelofibrosis' has the scientific objective of gaining insight in molecular-biological and environmental factors, that are involved in the development of malignant hematological diseases such as…
To identify new genetic defects in telomeropathies.