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Multi-parametric MRI in patients suspected for muscle invasive bladder cancer: a new local staging paradigm

The aim of this study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with an outpatient biopsy for histological confirmation, is a faster, safer, cheaper and therefore more cost-effective way to detect or…

Prediction aided tapering in reumatoid arthritis patients treated with biologicals

To assess the effect of adding a tapering decision aid on a dynamic flare prediction model to disease-activity-guided dose optimisation (DGDO) on the incidence of flares and medication use.

Development and validation of a psychological measure and derived short screener to
estimate the risk to develop personality disorders based upon the taxation of ultra-high risk
domains

The prognostic accuracy of combining these four criteria to predict the later development of personality disorders (with/without psychosocial breakdown) is investigated in a longitudinal study. From this, a selection of items with the strongest…