125 results
To compare the digestibility, bioavailability and subsequent muscle protein synthetic response to casein, with casein protein provided in an isolated manner versus casein in a milk matrix, in healthy elderly subjects
The first objective of this study is to gain insight in which neurocognitive and neurobiological processes underlie the development of externalizing behavior (in specific aggressive behavior) in the first two years of life. The second objective is…
Primary Objective(s): 1. To obtain preliminary data on whether (and to which extend) adjuvant chemotherapy for colon cancer results in (a) deterioration of contractile muscle properties and increased muscle fatigability, (b) increased inflammation…
Primary objective: Investigate the effects of acute stress on resting state and task-induced connectivity in the brain of healthy individuals and unaffected siblings of schizophrenia patients. Secondary objectives: - Correlate the endocrine stress…
The purpose of the present study is to investigate the effects of light therapy (with two different light boxes) on depression in people with intellectual disability (IQ *70 ) compared to standard care (care as usual).
The primary objective is to test the hypothesis that a protein-rich nutritional supplement (containing 45 g of dietary protein) prior to surgery acutely increases skeletal muscle and bone protein synthesis rates in older patients undergoing a hip…
To study the effectiveness of gut-directed hypnotherapy in the treatment of IBS-like symptoms in patients with inflammatory bowel disease.
To gain further insight into the interaction and possibly shared pathophysiological mechanisms of female-specific cardiovascular risk factors and events we will quantify white matter hyperintensities on brain MRI and assess endothelial function in…
The primary objectives are to investigate whether L-carnitine infusion may rescue lipid-induced insulin resistance and whether L-carnitine infusion is improving metabolic flexibility in the state of lipid-induced insulin resistance. Furthermore,…
We aim to investigate whether pulsatile flow in patients subjected to CPB preserves postoperative microcirculatory perfusion by prevention of a prothrombogenic profile and endothelial activation as are both present under non-pulsatile flow…
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
To determine the difference in secondary caries lesion development in tooth samples with simulated restorations from different restorative materials and to relate this to the microbial composition and acid production capacity of biofilm taken from…
Aim of this in situ study is to investigate the development of wall lesions in the presence of different interfacial gap sizes.
To study the effect of pectin in 5 different physicochemical states on ad libitum energy intake and possible underlying mechanisms; i.e. gastrointestinal hormones, gastric emptying rate, feelings of satiety and the method of fiber supplementation.
Not applicable
The primary objective of the study is to investigate whether local insulin supplementation augments the in vivo postprandial muscle protein synthetic response after protein ingestion and whether this response is differs between young and elderly…
For a possible (better) treatment of FOG a better understanding of the brainmechanism behind this phenomenon is needed. Previous studies showed some brain areas that are possibly involved in FOG.The aim of this study is to see whether we can induce…
The purpose of this study is to investigate basal sexual conditioning mechanisms among healthy males and females. This study will investigate how stimuli acquire or lose sexually rewarding properties. This knowledge may help in the treatment of…
The objective of the first part of the study is to assess whether circadian misalignment: - decreases energy expenditure and activity induced energy expenditure - alters substrate oxidation- alters feelings of hunger and satiety - alters food choice…
Objective: To study differences of (adipo) cytokine spectra in visceral and peripheral adipose tissue and to study the effect of caloric restriction on (adipo) cytokine production of these different fat tissues.