2921 results
To evaluate the effect of pneumodilatation (PD) on prolonged dysphagia after Toupet or Nissen fundoplication compared to sham dilatation.
To study the efficacy of end-ischemic DHOPE in reducing the incidence of NAS within six months after controlled DCD (Maastricht category III) liver transplantation.
The primary objective of this study is to determine whether targeted therapeutic mild hypercapnia (TTMH) improves neurological outcome at 6 months compared to standard care (targeted normocapnia) (TN).
To evaluate the incidence of incisional hernias after stoma reversal after preventive mesh placement compared to no mesh placement. Secondly the incidence of parastomal hernias will be recorded and complications caused by preventive mesh placement…
Primary Objective: The aim of this study is to assess the clinical value of intraoperative OCT (iOCT) for Descemet Membrane Endothelial Keratoplasty (DMEK) by comparing an iOCT-optimized surgical protocol (iOCT-p) with the current practice (CP-p),…
The primary objective of this study is to proof the concept that cisplatin-induced ototoxicity can be prevented by transtympanic STS containing gel application, through inserted grommets.The STS containing and blank gel formulations will be provided…
The main goal is to investigate whether COMET can be used as an intervention to reduce paranoia in patients with psychotic disorder and paranoid thoughts. An aim is also to see if the treatmenteffect is stable after eight weeks.
To test whether the Emma-app and/or a financial incentive can improve therapy adherence, clinical disease outcomes and quality of life in adolescents and young adults with a chronic health condition.
The current study has two aims. Firstly, to investigate the effectiveness and cost-effectiveness of 8 weeks of the E-health program, Featback, in comparison to Featback with online support from an expert patient, online support from an expert…
The current project aims (1) to unravel underlying mechanisms for the insomnia subtype that has a high risk to convert to depression by evaluating their profile of psychological traits, health history, life events, behavioral habits, environmental…
To assess the safety and efficacy of the paclitaxel drug-eluting balloon IN.PACT 014 versus conventional, optimal percutaneous transluminal angioplasty (PTA) for the treatment of patients with chronic total occlusions in the infrapopliteal arteries…
The goal of this study is to determine functional outcome and patient satisfaction between the Journey II and the Genesis II prosthesis. The results of this research will help optimize prosthesis selection, possibly resulting in higher patient…
To investigate the effect of subjective beliefs on motivated behavioral responses following frontal transcranial direct current stimulation (tDCS) in healthy volunteers.
Nowadays, many dislocated fractures of the distal radius will be treated operatively. However, a significant amount of dislocated distal radial fractures do not need operative treatment and will be treated by reduction and immobilization. Usually an…
This study aims to examine the effectiveness, feasibility, and applicability of the adapted and translated CR from Mullen and colleagues (2017), named Mindset, for students with psychotic problems in the Netherlands.
To determine the difference in increase in cycle endurance time after PR using NHF oxygen supplementation in patients during both exercise training and night time compared to patients using a conventional oxygen delivery systems.
The primary objective in the study is to explore the effect of three different amplitude settings (50%…
The purpose of our study is to test the effect of a computer-based cognitive behavioral intervention (called Cognitive Bias Modification, CBM) on affective symptoms in oncology patients. Here we are collaborating with the Oncology department of the…
Objectives:Primary:* To evaluate the safety and tolerability of single doses of DCR-PHXC Solution for Injection (SC use) (*DCR-PHXC*) inNHV (Group A) and in patients with primary hyperoxaluria (PH) (Group B).Secondary:* To characterize the…
This is the first project in The Netherlands aimed at testing the acceptability, feasability and effectivity of an online intervention aimed at the psychosocial functioning of adolescents with a visible difference. The aim is to 1) test if the…