2921 results
Primary objective: To determine if a single dose of SRT2379 attenuates the inflammatory response in normal healthy male subjects after exposure to low-dose endotoxin (LPS) Secondary objectives: (1) To determine PK of SRT2379 in normal healthy male…
To understand more of the learning principles of vegetable consumption in young children (2-4 years). The aim of this study is to investigate the effect of flavour nutrient learning on vegetable preference and intake. Primary Objective: To…
Primary Objective: Does the use of the laparoscopic insertion technique lower the incidence of malfunctioning CAPD-catheters at 6 weeks postoperatively? Secondary Objectives: Does the use of the laparoscopic insertion technique improve catheter…
To investigate whether an endothelin-1 receptor antagonist improves exercise capacity (peak V*O2) in adults with CHD or with mitral valve lesions who undergo cardiac surgery.
Primary ObjectiveThe primary objective is to show that fusion with the Valeo OL spacer produces similar improvement in MRDQ at all follow-up time points as compared to the same procedure with PEEK cages.Secondary ObjectivesTo show that the fusion…
The aim of this study was to investigate the effect of an antiseptic mouthwash and tongue hygiene on the concentration of volatile sulphur compounds and morning bad breath in periodontal healthy subjects.
The aim of this study is to investigate the possible consequences of generic-generic substitution of gabapentin, a frequently used anti-epileptic drug.
In patients over 60 years of age who have sustained a displaced femoral neck fracture, what is the rate of revision surgery at 24 months when a total hip arthroplasty versus hemi-arthroplasty is used as the surgical treatment? Hypothesis: We…
To investigate if there is a correlation between the peak GH concentrations after ingestion of gelatin protein and the peak GH concentrations after the two standard tests (GHST) in order to discriminate between GHD and non-GHD. To investigate the…
The main objective of the study is to investigate whether of the biolimus eluting and biodegradable polymer NOBORI* stent is non-inferior or even superior to the everolimus eluting XIENCE-V/XIENCE-PRime/PROMUS* stent in daily practice.
The central hypothesis of Switchbox is that control of homeostasis by the hypothalamus will be better preserved in the offspring of long-lived sibling who age in better health compared to their partners that show *regular* ageing. This, we…
Objective: To establish the effect of perinatal probiotics on the prevalence of allergic disease at the age of 5 or 6 years.
- To assess the safety and tolerability of FSH-GEX* following multiple dose administration by subcutaneous injection- To determine the pharmacokinetic profile of FSH-GEX* following multiple dose administration by subcutaneous injection- To assess…
The primary objective of the study is to investigate whether local insulin supplementation augments the in vivo postprandial muscle protein synthetic response after protein ingestion and whether this response is differs between young and elderly…
Primary Objective: (1) To study the efficacy of exercise therapy and CBT for reducing fatigue and improving activities and HRQoL in patients with PPS. Secondary Objectives: (2) To identify generic and disease-specific determinants of effects.(3) To…
ACT reduces the incidence of PTS after DVT. In the Dutch CBO-guidelines current therapy is adviced for 2 years after diagnosis because most PTS develops within 2 years after DVT, with a peak incidence in the first year.Some clinicians claim that one…
To determine the safety and effectiveness of Boston Scientific*s Everolimus-eluting coronary stent system (PROMUS Element*) for coronary revascularization in an unrestricted population compared to the Xience* Prime control.
Primary objective: To create diagnostic and treatment tools for navigation ability in stroke patients, that can be used in clinical practice.Secondary objective: To increase knowledge about the cognitive structure and neuroanatomical correlates of…
The primary objective of this clinical trial is to demonstrate the safety and effectiveness of the Combo Bio-engineered Sirolimus Eluting Stent (Combo Stent) compared to the commercially available TAXUS® Liberté® Paclitaxel-Eluting Stent (DES) in…
The objective of this study is to evaluate the short (1 month) and long term (6 and 12 months) efficacy of two versions of the computer-tailored nutrition education program in improving dietary intake patterns (i.e. (saturated) fat, energy and fruit…