15 results
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
The primary objective of the study is to determine whether AVIM therapy in combination with medical therapy is more effective at reducing ambulatory systolic blood pressure (aSBP) and to determine whether AVIM therapy is safe.
This study has been transitioned to CTIS with ID 2024-520305-39-00 check the CTIS register for the current data. Primary objective: to evaluate the efficacy of LSD 25µg every 3 days for 3 weeks in cCH. Additional objectives:- To evaluate the safety…
The primary objective of this study is to compare the mean binocular DCIVA at 66 cm under photopic conditions 3 months after cataract surgery, in a series of patients, who previously underwent myopic laser surgery, bilaterally implanted with the non…
The ultimate goal is to investigate whether aVNS can enhance cortical plasticity and improve functional outcomes during intensive rehabilitation programs in children with cerebral palsy. First, we aim to establish the extent of cortical plasticity…
Primary objectives:• To characterize the central inflammatory response to IV LPS by measuring biomarkers in CSF• To characterize the systemic inflammatory response to IV LPS by measuring biomarkers in blood • Characterize CSF/Blood ratios for each…
The primary objective is to examine the effect of twelve weeks supplementing daily one AstaPure® Oleoresin capsule on trans epidermal water loss (TEWL) in postmenopausal women. The secondary objectives are to investigate the effects on other skin,…
Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…
The primary objective is to evaluate the effectiveness of dietary nitrate in reducing muscle atrophy induced by bedrest. Secondary objectives include assessing its impact on insulin resistance, muscle strength, and cardiovascular function.…
Primary Objective: to assess brain kinetics of glutamate, GABA and dopamine and the associated functional connectivity of the mesocorticolimbic circuit during the absorption and elimination phase of JWH-018, as compared to the control condition.…
Primary Objective: To assess the acute subjective drug effects (good/bad drug effect, drug liking/wanting, anxiety), cognition (attention, working memory, information processing speed, verbal memory, verbal fluency, motor inhibition), and…
The primary objective is to determine whether stratified medical therapy guided by an adjunctive interventional diagnostic procedure (IDP) during the invasive management of patients with known or suspected angina but no obstructive CAD improves…
The main aim of the study is to compare the optimal protein intake of a protein with a high quality (milk) to the optimal protein intake of a protein with a low quality (wheat) in healthy older adults using the indicator amino acid oxidation (IAAO)…
The overarching objectives of this proposal are: 1) To evaluate the effect of noradrenergic modulation on type I potentials in wakefulness (vertex potentials), and NREM sleep (vertex sharp waves, K-complexes) and on dreaming in NREM sleep; 2) To…
The aim of this study is to compare the efficacy and safety of preoperatively placed Pericapsular Nerve Group block (PENG), Fascia-Iliaca Compartment Block (FICB) and Femoral Nerve Block (FNB) for patients with hip fractures in the ED.