382 results
Salmeterol has an inhibitory effect on both allergen and allergen/LPS induced inflammation in asthmatics while on maintenance treatment with low dose corticosteroids.
This international, multi-centre, double blinded, placebo-controlled, randomised clinical trial will be performed: To assess the effectiveness of one year of alternate days Levamisole treatment in a dose of 2.5 mg/kg in the prevention of relapses…
COMT and/or PRODH polymorphisms are debt to cognitive deterioration in velocardiofacial syndrome.
To investigate the difference in effectiveness of methylphenidate (MPH) in the treatment of adult ADHD patients with and without comorbid cocaine dependence.
Pain (physical discomfort) and challenging behavior are highly prevalent in nursing home residents with dementia. It has been shown that pain is undertreated in this group, and that psychosocial interventions for behavioral problems are, allthough…
In the Netherlands over 10.000 patients are diagnosed with head and neck cancer or lung cancer every year of whom 25-50% have comorbid anxiety or depression. Is a stepped care strategy applied in an oncological setting more (cost-)effective to…
The objective of the study is to assess the impact of a proactive policy of offering EA at the start of labour before maternal request in women with a child in occiput presentation allowed to try a vaginal delivery, on maternal pain reduction,…
1. DCS enhances the speed and size of effect of exposure therapy in panic disorder and OCD; 2. This DCS enhancement is independent of the nature of the anxiety provoking situations (OCD-related versus panic-related); 3. There is no difference in…
This study aims to answer two research questions: 1. Does web-based monthly monitoring using the Asthma Control Test (ACT) improve asthma control? Is this strategy cost-effective? 2. Does asthma management guided by the fraction of nitric oxide in…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
This study was therefore designed to determine whether cinnamon lower postprandial blood glucose, and insulin levels in subjects with type 2 diabetes or impaired glucose tolerance.
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
Detection of chronic pain in adolescents by self-report combined with advice from a school nurse will be efficient and effective.
It is expected that the new pre-thickened sip feed is as safe as and well-tolerated as standard sip feed thickened with a commercially available thickener.
The investigational anti-reflux formula will be equivalent to the currently marketed control anti-reflux formula with regard to intestinal tolerance during eight weeks in infants with regurgitation.