697 results
Patients with Type 2 diabetes have been shown to have an increased risk for developing cancer, especially obesity related cancers. There is some evidence that within the class of sulfonylureas there is a difference in cancer risk; gliclazide could…
the aim of this study is to compare two strategies that present a large contrast in the stimulation dosage, i.e. a high dosage of stimulation versus a low dosage of stimulation. Our study is designed to objectively compare the ongoing pregnancy rate…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
1. To determine the reproducibility and sensitivity of the Energy Cost of Walking test (ECWT) in boys with Duchenne muscular dystrophy, in comparison with the reproducibility and sensitivity of the 6-Minute Walk Test (6MWT); 2. To evaluate the 1-…
A postoperative retransfusion system is most effective in terms of allogeneic blood transfusion rates when in situ for maximum of 6 hours after major orthopaedic surgery.
We hypothesize that exogenous, enterally provided glutamine contributes substantially to the de novo synthesis of arginine in critically ill patients.
In general practices, proactive care for potentially frail older people with the use of Utrecht Periodic Risk Identification and Monitoring (UPRIM) and the use of a Geriatric Nurse Primary Care (GNPC) will result in better daily functioning in…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Two hypotheses will be tested. First, we expect parents in the experimental group, who drink as well as those who abstain from alcohol, to use more alcohol-specific socialization strategies than parents in the control group. Second, we expect that…
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius/ulna…
Missing doses and early discontinuation are two levels of inadequate drug adherence. Multidisciplinary interventions may improve adherence. We hypothesize that in patients with multiple sclerosis (MS) certain modalities or durations of care are…
Faecal transplantation from a healthy donor can restore the dysbiosis present in adolescents with refractory IBS, thereby inducing improvement of the IBS complaints.
A disease management approach to depression and anxiety in primary care patients with diabetes mellitus, asthma and/or COPD will result in reduced symptoms of depression and/or anxiety, better quality of life, less disease specific distress, better…
A goal directed nutritional support can reduce sarcopenia in surgical esophagus patients.
The TOF Cuff NMT monitor is as reliable as the TOF-Watch SX acceleromyograph for perioperative neuromuscular monitoring.
This study will evaluate the effectiveness of IPAS, with and without additional support, to improve objectively measured PA levels. We expect that IPAS will raise the level of PA more than normal care (UC) with a higher expected effect for IPAS +…
The hypothesis is that receiving additional counselling will lead to greater improvements in behaviour change compared to no additional counselling.