349 results
Patients with MEN-1 have a high risk of developing primary hyperparathyroidism (PHPT). Surgical removal of all pathological parathyroid glands is the only approach that provides definitive cure, however, the recurrence rate in patients with a MEN-1…
In a randomised, single-blinded, open trial, patients with GTS or CTD will be randomized for medical treatment (Risperidone) or behaviour treatment (exposure and response prevention, ERP). Risperidone has been shown effective in tic disorders, as…
S(+)-ketamine influences resting state fMRI in a dose-dependent fashion.
Stepped cased finding of women with increased fracture risk using questionnaires , bone densitometry and vertebral morfometry and treatment with bone sparing drugs of those with indcreased fracture risk in primary care reduces fractures.
The response in cerebral blood flow upon ingestion of a liquid meal differs between males and females.
Skin temperature can possibly affect the effect of scalp cooling. First a pilot study will be conducted to check the feasibility of the main study. The primary objective of the main study is to identify a cut-off score under which alopecia can be…
An intracutaneously sutured ileostomy may be more effective than a transcutaneously sutured ileostomy to reduce peristomal dermatitis, leakage and costs and to improve quality of life of patients with an ileostomy.
Accumulating data from both patients and animal models indicates that imbalances in the composition of the gut microbiota are related to obesity and its associated diseases However, the exact role of the microbiota and the mechanism mediating its…
In this study the hypothesis will be tested that gemcitabine has a radiosensitizing effect in addition to 131I-MIBG therapy which will lead to increased anti-tumour effect in neuroblastoma.
31-3-2014 Hypothesis: Early administration of 5 mg of Metoprolol is associated with a relative 20% reduction in infarct size as measured by cardiac Troponin-T, a total of 408 patients will be enrolled and randomized. Interventions: 5 mg intravenous…
To assess the tolerability and efficacy of the addition of oral lenalidomide to standard induction therapy.
To evaluate variations of androgenicity and androgen (re) activity in (apparently) eugonadal women by using CAG repeat length polymorphism ([CAG]n) of the androgen receptor, free testosterone levels, 2D:4D ratio and attention for erotic stimuli (…
Social skills training will increase the social and communicative skills in daily life situations of children with ASDs as compared to children who do not follow such training. Additionally, training parents and teachers will increase generalisation…
The internet intervention will enhance empowerment, perceived justice, wellbeing and knowledge of personal injury victims during claims settlement.
It is predicted that the PDE5 inhibitor vardenafil will reverse memory impairments induced by THC if the latter depend on glutamatergic neurotransmission. It is expected that the cholinesterase inhibitor rivastigmine will reverse THC-induced memory…
5-ASA and UDCA have a chemopreventive potential in UC.
To determine whether a second IVIg course in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, mechanical ventilation, length of hospital and ICU…
HIV-induced immune activation through intestinal bacterial translocation can be modulated by statins.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
The multidisciplinary integrated care programme is effective in improving self-help, social participation and experienced quality of life of elderly stroke patients. And is effective on the reduction of burden of care of carers.