310 results
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
increased gastric distention will induce greater activation in satiety related areas
Self monitoring of the ECG by the patient contributes to the correct diagnosis, reduces the frequency of cardiology consultations and leads to less side effects and lower dosage of medication. Patients become more confident and gain more insight…
(1) SNP will reduce the occurrence of psychomimetic side effects during exposure to low]dose ketamine; (2) SNP will reduce the ketamine]induced increase in blood pressure and cardiac output; (3) SNP is without effect on ketamine]induced pain…
Hypothesis: arterial oxygen concentrations induce dose-dependent hemodynamic and microcirculatory changes during oxygen supply in mechanically ventilated, post cardiac surgery, ICU patients. Aim: In this study we want to investigate the effects of…
Endoscopic resection of Barrett's neoplasia with the Captivator EMR device is effective and safe
In the current study we will apply the Elfitor monitor and collect its derived parameters during nociceptive stimulation in healthy volunteers without and with the administration of a low-dose opioid analgesic. Our study aim is to assess whether the…
We hypothesize that offering patient after general surgery water ice cream will reduce the side effects of sore throat and foul smell and in general increase the quality of recovery.
Via a peritumoral injection of ICG-nanocolloid, lymphatic mapping of oral cavity tumors can be performed
Anti-TNF treatment (infliximab (IFX), adalimumab (ADA)) has become standard therapy for refractory pediatric and adult Crohn¡¯s disease (CD) patients, and is used for the induction and maintenance of remission. When effective, clinical and…
Applying triage and case management for people with multiple complex problems in the Northern district of Amsterdam will improve their level of participation, their self-sufficiency and their health, and result in reduction of health care costs.
Diabetes Mellitus (DM) patients with angiographically intermediate coronary lesions remain at risk for future MACE events, including those patients with fractional flow reserve (FFR) negative lesions. Use of FFR measurements combined with Optimal…
After two months, podopostural therapy has more effect on back and leg pain in people with (radiating) leg pain on the side where the ilium is higher than the other side compared to those with (radiating) leg pain on the side where the ilium is…
1) Patients with substance abuse problems differ in levels of impulsivity, craving and resting-state EEG as compared to healthy controls. 2) A theta/SMR- based neurofeedback intervention can reduce symptoms of drug-seeking behaviour by modulating…
Hypothesis 1: We expect to find an approach bias in forensic sexual offenders and in sexual addicts. Hypothesis 2: The proposed intervention will cause a decline in approach bias in forenisc sexual offenders and sexual addicts, compared to the…
Our hypothesis is that radiotherapy can achieve a pain-reducing effect of at least 20% after 6 months.
This study will investigate the feasibility of HRD test in metastatic lesions of different sites among breast cancer patients who will start treatment with chemotherapy. The sites of metastatic lesions that will be investigated are: liver, lymph…
The aim of this pilot study is to compare two physiotherapeutic rehabilitation strategies in patients who undergo hip arthroscopy for femoroacetabular impingement. Postoperatively, group one will visit the physical therapist two times a week and…