107 results
Primary Objective: To study known heartfailure biomarkers (proteomics, microRNAs and metabolomics) for the detection and prognosis of cardiotoxicity in patients receiving antineoplastic therapy, and to discover predictive biomarker (values). In the…
The purpose of this study is to see if we can predict which patients with CTS are eligible for an injection, and which should be directly referred to a surgeon. This to shorten the period of the patient's symptoms and to save healthcare costs.
This study aims to investigate the effect of switching from Atripla® to Eviplera® on neurocognitive performances (neurocognitive testing) and imaging (functional MRI scanning) in virologically suppressed HIV-infected patients and stable on atripla.
The objective is to investigate the correlation between bacterial/viral gut infections and acute appendicitis in children.
Primary Objective: To assess the hemodynamical effects of administration of AS in FGR fetuses and to compare these effects with those that occur in appropriate for gestational age (AGA) fetuses. Secondary Objective(s): To investigate the effect of…
The primary objective of this study is to explore the PSA response rate to cabazitaxel in mCRPC patients who have progressed to docetaxel and to correlate the PSA response to AR-V7 expression in CTCs. Exploratory objectives include documenting the…
The aim of our project is to perform a novel mass screening to detect CD in 12 months-4 years old children who visit the YHCCs in a well-described region in the Netherlands, to show that it is feasible, efficient, cost-effective and well accepted by…
Using technology for improving diagnostics of non-specific lower back pain by physiotherapists
To study the effects of varying amounts of air and patient position on oesophageal pressure measurements in children with and without lung injury.
To determine whether the attenuated salivary cortisol response in children with asthma can be explained by the maintenance use of inhaled cortiocosteroids, the chronic inflammatory disease, or the attenuated exercise capacity.
In this study we will explore changes in the hepatic function after stimulation of hepatic cells with an oral food challenge, the **hepatocyte reserve capacity**. Moreover, we will explore potential differences in the hepatocyte reserve capacity…
(i) identification and cellular characteristics of red blood cells from patients with altered ion homeostasis and delivery of novel and easy-to-use diagnostics for rare anemia*s, for patients with: a) a known primary defect in the ion channels of…
The main objective of this study is to assess the effects of rituximab (RTX) as a rescue therapy for therapy resistant progressive IMID- IP patients. Specifically there is an objective assessment of (1) pulmonary function tests (PFTs) and (2)…
Primary objectives: To examine the ability of functional imaging signal changes over the course of treatment to distinguish patients with and without local recurrenceSecundary objectives:To examine the correlation between the different imaging…
The primary objective of the PASSENGER study is to investigate any relationship between changes in SonR1 augmentation and a change in patients* exercise capacity as assessed by the 6 Minute Walk Test.
This study will assess the presence of prediabetes (defined as glycated hemoglobin [HbA1c] greater or equal to 5.7% and greater or equal to 6.4%, or fasting plasma glucose [FPG] greater or equal to 100 mg/dL [5.6 mmol/L] and greater or equal to 125…
Primary objective We investigate whether observers* inferring accuracy differs when the consumer is in the presence of a friend compared to being completely alone. We test whether observers* brain activations during inferring observation differ…
This study will investigate whether bone marrow-derived allogeneic MSCs, as administered by the nasal route, can induce the formation of neuronal tissue and restore brain function in neonates who suffered from perinatal arterial ischemic stroke (…
The primary objective is to evaluate the lab transferability of the exercise model as used in the GRINTA! study. This will be achieved by comparing the effect of exercise on biomarkers in blood, urine and saliva in two different laboratories. These…
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end of coronary angiography or PCI.