117 results
Primary Objective:The primary objective in the current trial is to use graph theory to examine how the organization of the functional brain network may be altered by the administration of methylphenidate. The main question we intend to answer in…
Clarify the effect of 5T polymorphism with or without another CF causing mutation on the other allele, on the CFTR function.
To compare the effect of IT dexamethasone versus IT gentamicin on number and severity vertigo attacks.To compare the effects of IT dexamethasone with IT gentamicin on hearing function, functional level scale and aural fullness.
Human intestinal biopsies will be used to further develop an in vitro intestinal model. This model will the be used for future research to study the effect of nutreints and drugs on intestinal function. The human biopsies will be compared with…
The primary objective is to evaluate health related QoL under an oral sequential treatment with natural steroid hormones: Duogestan®. The secondary objective is to evaluate the bleeding patterns over a one-year period.
Evaluation of therapeutic safety and clinical efficacy of MSC transplantation in septic shock.
Primary objective1. To examine the association between the use of haloperidol and the acute changes in serum glucose and QT interval in elderly patients undergoing orthopaedic surgery.Secondary objectives1.To examine the association between the use…
Objective of the study:Investigating with use of the classical coagulation tests on one hand and with the ROTEM on the other hand what is exactly becoming disturbed in the coagulaton because of bleeding during surgery of the aorta abdominalis,…
Objective: Main objective of this study is to compare the area under the MPH saliva concentration versus time curve (AUC) following ingestion of immediate and sustained release formulations of MPH in children with ADHD. Secondary objectives are: 1.…
Primary: to investigate whether applying a conservative treatment for an unstable ligamentous skiers thumb is equal to surgical repair. Secundary: to calculate the sensitivity and specificity of standardised accurate physical examination when…
To perform a comprehensive analysis of the cellular infiltrate in lesional AD skin, using state of the art immunohistochemical techniques.
Primary objective 1. To examine the association between the use of haloperidol and the acute changes in fastening serum glucose and QT interval in elderly patients undergoing surgery. Secondary objectives 1.To examine the association between the use…
To study the toxicity, efficacy and immunogenicity of naked DNA vaccines encoding the shuffled HPV 16 E7 gene products (TTFC-E7SH) in advanced-stage patients with squamous cell carcinoma of the anogenital or the head and reck region.
The primary objectives are: 1. To assess BBB integrity in MPS IIIB patients by estimating the CSF AI.2. To determine the BBB transfer coefficient by DCE-MRI in MPS IIIB patients.The secondary objectives are: 1. To describe the relationship between…
The primary aim of this project is to define the role exacerbations play in the pathophysiology of COPD. Moreover, the study has the aim to determine the long-term effects of PR and the natural course of the disease. The unique design of MCC will…
To study the influence of a prior opening wedge HTO on the results of a TKA.
The primary objective of this study is to demonstrate that the IOP-lowering efficacy of Travoprost Ophthalmic Solution, 0.004% (preserved with POLYQUAD) is noninferior to Timolol Ophthalmic Solution (0.5% or 0.25%) in pediatric glaucoma patients.
To compare the accuracy of syndesmotic reduction on an axial CT-scan postoperatively (reflecting syndesmotic malreduction) after syndesmotic positioning screws versus open reduction and fixation of the posterior malleolar fragment in AO Weber-C…
The primary aim of this project is to examine the impact of heart failure on functional sympatholysis. The second aim of this study is to examine whether nitrate supplementation can improve the effects of functional sympatholysis in heart failure.
Analyze processes related to DNA-damage in oocyte development and early-developmental stage embryos from BRCA1/2-mutation carriers compared to controls, using immunohistochemistry and RNA-Seq technology.