92 results
Primary objectives: - To evaluate the toxicity and feasibility of a preemptive minor H ag UTA2-1 peptide-loaded, PD-L silenced donor DC vaccination.- To evaluate the effect of a minor H ag UTA2-1 peptide-loaded, PD-L silenced donor DC vaccination on…
We hypothesize that verapamil reduces progression from paroxysmal to persistent AF, improves rate control, exercise tolerance and quality of life and reduces costs compared to metoprolol.
To assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer*s disease-causing mutation by determining if treatment with the study drug slows the rate of progression…
To study the effect size of FMT after a 3 weeks course of budesonide as induction therapy in patients with active ulcerative colitis despite previous therapy. The purpose of the pre-treatment is to reduce active inflammation prior to donor feces…
Primary Objective:The primary objective in the current trial is to use graph theory to examine how the organization of the functional brain network may be altered by the administration of methylphenidate. The main question we intend to answer in…
Clarify the effect of 5T polymorphism with or without another CF causing mutation on the other allele, on the CFTR function.
To compare the effect of IT dexamethasone versus IT gentamicin on number and severity vertigo attacks.To compare the effects of IT dexamethasone with IT gentamicin on hearing function, functional level scale and aural fullness.
Evaluation of therapeutic safety and clinical efficacy of MSC transplantation in septic shock.
Primary objective1. To examine the association between the use of haloperidol and the acute changes in serum glucose and QT interval in elderly patients undergoing orthopaedic surgery.Secondary objectives1.To examine the association between the use…
Objective of the study:Investigating with use of the classical coagulation tests on one hand and with the ROTEM on the other hand what is exactly becoming disturbed in the coagulaton because of bleeding during surgery of the aorta abdominalis,…
Objective: Main objective of this study is to compare the area under the MPH saliva concentration versus time curve (AUC) following ingestion of immediate and sustained release formulations of MPH in children with ADHD. Secondary objectives are: 1.…
Primary: to investigate whether applying a conservative treatment for an unstable ligamentous skiers thumb is equal to surgical repair. Secundary: to calculate the sensitivity and specificity of standardised accurate physical examination when…
To perform a comprehensive analysis of the cellular infiltrate in lesional AD skin, using state of the art immunohistochemical techniques.
Primary objective 1. To examine the association between the use of haloperidol and the acute changes in fastening serum glucose and QT interval in elderly patients undergoing surgery. Secondary objectives 1.To examine the association between the use…
To study the toxicity, efficacy and immunogenicity of naked DNA vaccines encoding the shuffled HPV 16 E7 gene products (TTFC-E7SH) in advanced-stage patients with squamous cell carcinoma of the anogenital or the head and reck region.
The primary objectives are: 1. To assess BBB integrity in MPS IIIB patients by estimating the CSF AI.2. To determine the BBB transfer coefficient by DCE-MRI in MPS IIIB patients.The secondary objectives are: 1. To describe the relationship between…
The primary aim of this project is to define the role exacerbations play in the pathophysiology of COPD. Moreover, the study has the aim to determine the long-term effects of PR and the natural course of the disease. The unique design of MCC will…
To study the influence of a prior opening wedge HTO on the results of a TKA.
The primary objective of this study is to demonstrate that the IOP-lowering efficacy of Travoprost Ophthalmic Solution, 0.004% (preserved with POLYQUAD) is noninferior to Timolol Ophthalmic Solution (0.5% or 0.25%) in pediatric glaucoma patients.
To compare the accuracy of syndesmotic reduction on an axial CT-scan postoperatively (reflecting syndesmotic malreduction) after syndesmotic positioning screws versus open reduction and fixation of the posterior malleolar fragment in AO Weber-C…