58 results
The main goal of this study is to investigate the influence of STN DBS on the cognitive processes of reward processing and selective visual attention.
The main objective of the study is to investigate the muscarinic cholinergic system as a biological substrate for cognitive dysfunction in schizophrenia. Since cognitive dysfunction is the most disabling and untreatable characteristic of…
The objective of our study is to investigate the relationship between electrical stimulation of the central nervous system (VNS) and reward-based selective attention. In order to do so, we will ask subjects to complete a set of tasks on a standard…
We propose to investigate the effect of administering a broad-acting, potent immune suppressive agent early in the course of the disease as this may prevent neuronal damage caused by low-grade inflammatory processes in the brain. It is expected that…
The objective of this pilot study is to investigate wether:- Increased Hb levels prior to the operation can prevent blood transfusions preoperative, blood transfusions have a negative effect on the survival of cancer patients- Treatment with…
To study the clinical and radiological outcomes 20 years after operative or conservative treatment for an ACL rupture
The objective of this study is evaluation of an awarenessprogram on sensory processing Issues on effectiveness and efficiency with regard to quality of life.The central researchquestion is: what are the effects on experienced quality of life of the…
Primary: To compare the efficacy of aripiprazole with placebo in the suppression of tics in children and adolescents (7-17 years) with a diagnosis of Tourette*s Disorder. The primary efficacy measure is change from Baseline to endpoint (Week 8) on…
Primary:-To assess the impact of educational programme on implementation phase adherence in patients taking apixaban for Stroke Prevention in Non-Valvular Atrial Fibrillation (SPAF) at 24 weeks.Secondary:-To identify predictive risk factors linked…
Evaluation of the effect of pre-TURBT intravesical instillations of MMC mixed with TC-3 Hydrogel on bladder lesion(s) of NMIBC patients.a. Comparison of the effect of pre-TURBT instillations with MMC mixed with TC-3 Hydrogel on bladder lesion(s) to…
The purpose of this study is to demonstrate the beneficial effect of ivabradine on plaque burden, morphology and composition, as well as on arterial wall shear stress (WSS) in patients with CAD who have a clinical indication for coronary angiography…
The primary study objective is to assess whether TCS in cataract patients is a predictor of postoperative VA and if so, whether it is a better predictor than currently routinely used measurements, as represented by preoperative VA measurement…
1. Measurement of the hsTnT value in patients undergoing elective ECV in order to determine AMI.2. Identification of characteristics related to an minimal increase of hsTnT value (<14 ng/L).
To suppress low-level viremia to a level below 50cp/mL in patients using cART by switching their current non-nucleoside reverse transcriptase inhibitor (NNRTI) or PI to DRV boosted with ritonavir (RTV) (DRV/r). Secondary objectives are to reduce the…
The primary purpose of this study is to compare alignment criteria in the Oxford Partial Knee using conventional instrumentation and Signature Custom Guides. Secondly it is questioned whether the Signature technology can reduce the number of…
To assess the effect of SLT on the frequency of soft (stool of type 3, 4 or 5 on the Bristol Stool Form Scale (BSFS)) complete bowel movements (SCBMs) and SCBMs non-straining (NS) per week in subjects taking World Health Organisation (WHO) step II/…
To compare the effects of Elevate Posterior procedure versus sacrospinous ligament fixation on pelvic floor function.
A Cross-sectional Study of Renal Function in Treatment-naïve, Young Male Patients with Fabry Disease
The objectives of this study are (1) to document renal function and other Fabry disease manifestations across age in treatment-naïve, young male patients with Fabry disease; and (2) to provide a reference group for comparison with interventional…