25 results
It is our hypothesis that one week of plaster cast treatment will give a better functional outcome score as Patient Rated Wrist Evaluation (PRWE) and a lower pain score at 6 weeks post injury and will be less costly as compared to the control group…
This study has a strong explorative and qualitative approach and set-up. Please note that the goal of the study is to further identify possible areas for innovation for professionals, patients and their partners. The aim for this study is NOT to…
Primary objective:1. To identify the components in human milk (e.g. nutrients, oligosaccharides, fatty acids and (pathogen specific) immunoglobulins) that have a protective effect against respiratory tract infections during the first year of life.…
To investigate the effects of atrial pacing on right ventricular function and hemodynamics after open heart surgery.
Primary:To compare the efficacy of abrocitinib 200 mg once daily (QD) versus dupilumab (as per label guidelines) in adult participants on background topical therapy with moderate to severe atopic dermatitis (AD).Key SecondaryTo compare the efficacy…
The disappearance of the main symptoms of the COVID*19*induced pneumonia within 5 days after the initiation&…
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Objective: To assess whether angiotensin receptor blocker (ARB) use is beneficial in the early phase of the disease, to prevent lung oedema and damage in high risk patients with a proven COVID-19 infection.
The objective of this study is to collect additional data on the performance and safety of the slowly-resorbable TIGR® mesh in patients undergoing TEP for IGRP. The study endpoints are described below.
Primary Objective:To verify the accuracy and performance of the GlycostatTM System including its ability to secure good glycemic control by means of its algorithm. The accuracy of Glycostat, expressed by MARD (Mean Absolute Relative Difference), the…
The primary objective is to determine the safety, tolerability and preliminary efficacy of repeated intrathecal administration of NurOwn® (MSC-NTF: Autologous Mesenchymal Stem Cells [MSC] Secreting Neurotrophic Factors [NTF]) given three times at…
Primary* To compare TFFS of patients with progressive, advanced, kinase inhibitor naïve, RET-mutant MTC treated with LOXO-292 versus cabozantinib or vandetanib.Secondary* To compare other efficacy outcomes, based on RECIST 1.1 criteria, observed in…
To test the hypothesis: the mode of action of benralizumab being ADCC will target both resident and inflammatory eosinophils whereas mepolizumab only targets inflammatory eosinophils. This will achieved by a head-to-head comparison of the presence…
The key objective of the pilot study is to test the effectiveness of a desk-based lighting intervention to sustain 25(OH)D levels of office workers during autumn/winter months. The secondary objective is to explore the correlations between changes…
PRIMARY OBJECTIVE To characterize the pharmacokinetics (PK) of single doses of solriamfetolin pediatric subjects with narcolepsy.SECONDARY OBJECTIVE To assess the safety and tolerability of single doses of solriamfetol inpediatric subjects with…
To determine the pre-liminary efficacy of ultra-low dose radiotherapy for COVID-19 related pneumonia with respiratory insufficiency.
Primary:Long-term safety of nivolumab in participants on treatment and in follow upExploratory:To follow participants who have completed therapy and are in or have completed follow-up on a parent study investigating nivolumab or nivolumab…
To characterize the presence of anti-Covid-19 IgM and anti-Covid-19 IgG in volunteering employees of the Department of Gastroenterology and Hepatology of the Erasmus MC.
The objective of this single arm interventional study is to determine if renal denervation performed in the distal main and first order branch renal arteries is as effective in reducing blood pressure as the procedural approach used in the SPYRAL…
To determine the effect of lidocaine on the main symptoms of COVID-19.