250 results
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
The study will assess drug-induced change in performance in divergent thinking and goal-directed behaviour when comparing psilocybin to placebo, before and after an induction of stress. Additional study parameters include frontal-subcortical…
Feasibility and reliability of prehospital triage in patients with thoracic complaints/pain appropriate to a suspicious ACS
This study is designed to give insight into the effects of an educational program about organ donation on lower-educated adolescents and how these effects were achieved. We expect participants to have a higher intention to register after receiving…
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research
The dutch language version of the PRHWE and the Quick DASH questionnaire are valid to use in patients with hand and wrist complaints
The absolute bioavailability of oral imatinib (Glivec®) at steady state can be calculated using LC-MS/MS after concomitant administration of a single 100 µg microdose of stable isotope labeled imatinib (imatinib-d8).
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
"De Nieuwe Toekomst" will empower female victims of intimate partner violence by making them financial independent which reduces the risk of intimate partner violence victimisation
To determine the influence of optical quality on perimetry for phakic and pseudophakic healthy and glaucoma patients. To determine the influence of CLE on perimetry and optical quality for PAC patients.
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
Adolescence represents a crucial stage in the maturation of executive functioning (e.g. working memory and inhibition) and mental health (i.e. behavioral and emotional functioning, and self-concept), which both are important predictors of academic…
Vibrotactile feedback from a 'smart' fork reduces the eating rate of a teenage girl suffering from brain damage that causes her not to detect hunger or satiation
We hypothesize that in healthy individuals with Early-life stress (ELS), THC, which directly targets the endocannabinoid system, is more effective than hydrocortisone in improving stress adaptation and extinction learning in an experimental model of…
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…