213 results
This study consists of two phases. For more information about the study layout, see page 13-16 of the research protcol.The aim of phase 2:- To compare two different sentinel node techniques in patients, suspicious for endometrial cancer. The main…
By adding Cetuximab to standard treatment, we hope to prolonge progression free survival
To evaluate if 11C-PiB is able to detect amyloid deposits in affected other organs and tissues in patients with systemic amyloidosis and to correlate the uptake of 11C-PiB in the different organs to laboratory parameters, biopsies and other imaging…
Primary objective phase II:To explore if there is an indication of a positive effect on local control rate of adding Cisplatin to local reirradiation and hyperthermia to patients with local regional recurrent breast cancer in previously irradiated…
This investigation aims to test a new, better and faster method voor measurement of the LVEF, that does not depend on technetium. The method relies on the tracer Gallium-citrate, a well-known molecule that is available in unlimited quantities in-…
The main objective of this study is to assess the efficiency of oxytocin compared to placebo as an addition to the exposure sessions in the treatment of PTSD. We hypothesize that adding oxytocin to exposure in TF-CBT produces acute changes in…
The main objective of the study was to prove the effectiveness of cryoablation in palliating pain and correlate the patients with a matched group of the Dutch bone metastasis study. The secondary objectives are to determine the accuracy of cryoprobe…
To compare the pharmacokinetic profile of uracil in cancer patients and healthy volunteers
Onset of effect of systemic therapy to enhance bone density (eg, bisphosphonates) is not immediate and may not adequately protect subjects with decreased bone density from fracture.Bisphosphonate therapy will typically require 2 to 3 years of active…
The primary objective of this study is to test safety and performance of the APD Perfusion Measurement Catheter & Monitor for the measurement of gut perfusion in humans. The secondary objectives of this study are to assess the normal values…
This study will investigate whether oligometastatic triple negative or BRCA1/2 related breast cancer can be treated effectively with a multimodality approach including induction chemotherapy, and whether high dose alkylating chemotherapy can improve…
STUDY OBJECTIVESPrimary objectiveTo assess the safety, tolerability and local tolerance of two different intravenous infusion doses over 72 hours of a new dosing regimen and a new formulation of MCI-186 in subjects with acute ischemic stroke.…
Objective: The primary objective of this pilot study is to compare FDG-PET-CT with HR-CT alone and to HR-CT and galactomannan test together for early diagnosing IFIs in neutropenic patients.
Primary Objective:to clinically use and validate the optimized Raman probe in a patient database in order to differentiate between benign and malignant bladder lesions in vivo.Secondary objective:to develop an algorithm to predict tumor grade in…
The statistical analysis will evaluate the correlation of Baseline NGAL and BNP levels -alone and together - with the clinical outcomes of hart-failure (HF-related adverse clinical outcomesthrough Day 30 and Day 90. The cut-off and estimated…
To evaluate the effectiveness of the Chartis System in selecting subjects with heterogeneous emphysema who will achieve Lung Volume Reduction from Endobronchial Valve therapy.
The primary objective of this study is to establish the sensitivity and specificity of an oral uracil loading test as a potential screening tool for DPD deficiency
Primary Objective: Description of the 1-year overall survival after chemo-radiation therapy with or without panitumumab in irresectable carcinoma of the oesophagus. The control arm is used to validate whether the historical cohort used for…
To determine the test-retest variability of quantitative hypoxia imaging with FAZA-PET, both in untreated subjects (track A) and during radiotherapy (track B). The purpose of this study is to validate FAZA-PET as a selection criterion for…
To demonstrate the accuracy of FLT-PET to be an early response parameter for haematological recovery.