59 results
Objective of the study: The primary objective of this study is to assess the efficacy See primary endpoints, section 7.1 of endoluminal stent grafting and BMT compared to BMT alone in the treatment of uncomplicated acute type B aortic dissections.
Primary objective:1. Reduction of hospitality duration in patients with CAP treated with intravenous dexamethasone. Secondary objective:1. Reduction of the use of intravenous antibiotics in patients with CAP treated with intravenous dexamethasone.2…
The main objective of the study is a head tot head comparison of the everolimus coated XIENCE-V* stent with the paclitaxel coated TAXUS* stent in order to observe whether there is a difference in clinical outcome between both stents. Efficacy of…
Are there differences is efficacy, side effects, tolerance en costs in patients with early RA in treatment with COBRA-light compared with COBRA according to BeSt?
What is the long-term clinical benefit of best medical practice with and without adjunctive SCS Therapy in patients with chronic diabetic neuropathic pain?
The primary objective of the study is to prospectively determine whether fluoropyrimidine-induced toxicity is preventable by dose adjustment prior to start of the first administration based on the polymorphic status of the DPYD*2A polymorphism in…
To determine the optimal therapy for patients with pT1-2 pN0 oral and oropharyngeal cancer
To demonstrate superiority of tiotropium vs. salmeterol in reducing exacerbations which are an important patient outcome because they are a major cause of morbidity from COPD. In addition, they are associated with a more rapid decline in lung…
NSAIDs are drugs that are often prescribed to patients with rheumatic or orthopedic diseases. They seem to be at a greater risk for falls than healthy persons because of their disease, age and medication use. Therefore it is very important to keep…
The objective of this study is to assess the difference in micromotion of the Stanmore hip prosthesis (form enclosed), using two different bone cements. We hypothesise that the newly marketed bone cement Refobacin- gentamycine has the same in vivo…
This new developed knee prosthesis will be compared to the standard scorpio PS knee prosthesis. In this comparison it will be examined if the changes in design really do improve function and deminish pain. Allso patella tracking and patella tilting…
Objectives1. Determine efficacy of adalimumab as the first biologic agent or after previous use of other anti-TNF blocking agent. Efficacy will be evaluated by means of the ASAS 20% response criteria.2. Determine the efficacy of adalimumab on…
The aim of this study is determine the efficacy and safety of Metformin as a weight reducing drug in the euglykemic, obese paediatric population.
To assess the performance of the ConforMIS for the repair of the osteoarthritic knee with damage in either the lateral or medial compartiment of the knee.
efficacy of lanreotide LAR in controling total liver volume in patients with hepatic cysts as a result of ADPKD or PCLD
To study in a large randomised double-blind trial, if the administration of levothyroxine at bedtime significantly changes TSH and thyroid hormone levels compared to morning administration. Furthermore we want to evaluate the change of quality of…
The objective of this study is to assess the difference in micromotion of the Exeter hip prosthesis, using two different bone cements. We hypothesise that the newly marketed bone cement Refobacin- gentamycine has the same in vivo properties as the…
The primary objective of the study is to demonstrate non-inferiority of an insulin regimen using insulin glargine as the basal insulin with Exubera as the mealtime insulin, compared to a regimen using insulin glargine as the basal insulin and…
Primary Objective: The objective of this project is to explore the role of adenosine receptor stimulation in the protective effect of rosuvastatin against ischemia-reperfusion injury after ischemic exercise of the forearm.Secondary Objective(s):…
proof of safety of the Style 410 silicon breast implants