120 results
The objectives are firstly that Love is... promotes the healthy sexual development by increasing knowledge and positive attitudes towards sexuality. Secondly, characteristics of adolescents who do not improve from the general prevention program are…
To assess the prevalence of LDL-C >1.8 mMol/L in a subgroup of very high risk patients with ASCVD, who remain at a very high-residual risk for ACS, despite treatment with high-intensity statins in combination with ezetimibe. This subgroup of…
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
Primary objective: 1. To prove the concept that 90-day treatment with probiotics can restore microbiome composition and diversity in patients treated for community-acquired pneumonia. Secondary objective: 1. Investigate possible differences in…
Aim of this assessment is to explore the course (persistence, remission and onset) of AH and to investigate associations with other psychic experiences, anxiety and depressive symptoms, risk factors (trauma, cannabis), protective factors (coping…
To assess the additional value of a five day comprehensive assessment and intervention program on exercise and lifestyle followed by a six months maintenance program in primary care compared to the usual care program after solid organ…
The main goal of the current project is to adapt an existing stress reduction intervention (an e-health application) to the needs of women with a lower educational level and/or low SES, to enrich it with additional smoking cessation components, and…
To compare the effect of a HCPAP with LCPAP on oxygenation in the first 5 minutes during stabilization in preterm infants at birth.
Primary Objective: To describe the sleep and arousal patterns of firstborn infants between two and six months of age in day-care compared to home settings during and after the transition from home to day-care. Secondary Objective: To identify…
(protocol section 2) This phase 1 study aims to assess the safety and tolerability of monoclonal antibody TB31F administered intravenously or at escalating dose levels or subcutaneously in healthy, malaria naïve, adults. This study will also…
Our primary objective is to compare the short and medium term (up to 6 months) clinical results in pain and function of the Bauerfeind SecuTec OA brace with only conservative treatment (no brace) in the management of patients with medial knee OA and…
The primary objective of this study is to assess the effectiveness of myo-inositol supplementation to prevent pregnancy complications in women with PCOS. Secondary objectives are to evaluate the impact of supplementation on maternal (mental) and…
To investigate whether treatment with edoxaban leads to a decrease in incidence of leaflet thickening and is clinical efficient and safe.
Primary aim1) To investigate what proportion of levothyroxine users aged 60 years and older can withdraw from levothyroxine treatment successfully, defined as having normal fT4 levels and TSH levels <10 mU/L at 52 weeks after start of the…
This study has been transitioned to CTIS with ID 2024-511010-21-00 check the CTIS register for the current data. To prevent the development of chronic postoperative pain after inguinal hernia surgery and knee replacement surgery and to to further…
Is targeting an ACT > 400 seconds equivalent compared to an ACT > 480 seconds with respect to PRBC transfusion rates during hospitalization in patients undergoing cardiac surgery with cardiopulmonary bypass?
We would like to investigate whether GOS benefically alters the microbiota composition and -activity of the colon (not only faeces as done previously). This has not been done before by performing colonoscopies in a physiological condition and…
The primary aim of the study is to increase knowledge about the short and medium term effect of an intensive period of (organised) exercise on the level of HbA1c in the blood of diabetics. This can help caregivers in giving lifestyle advice to…
This trial aims to investigate if peroperative administration of TA can reduce the peroperative and postoperative hemorrhage rates in laparoscopic sleeve gastrectomy.
Main objectiveComparison of:- circulating B cell subsets,- immunoglobulin subsets,- B cell functionality (by means of ex vivo challenges),- and other relevant immune cellsbetween young healthy donors (aged 18-25 years), elderly healthy donors (&…