149 results
Should low-dose aspirin be continued up until the day of CABG or OPCAB surgery?Should TxA be used for all at-risk CABG or OPCAB surgery?
This study aims to evaluate the efficacy of an extensive eSupported lifestyle program in reducing physical risk factors.
The percentage of HRMO Enterobacteriaceae of hospitalized patients at time of admission.
Objective: The main objective is to demonstrate superiority of the intravesical overnight instillation of gentamicin versus oral antibiotic prophylaxis in reducing the number of recurrences of UTI and extending the time-interval to a next UTI, in…
Primary objective is to investigate if donor feces infusion is effective in eradication of ESBL producing Enterobacteriaceae in the large intestine. Secondary objective is to determine whether ESBL decolonisation of the large intestine actually…
This study has two goals:1. Investigate the cellular and humoral immune response of immune compromised travellers compared to the healthy traveller.2. Investigate the epidemiology of travel related infectious diseases in a population of dutch…
Primary objective: To investigate whether butyrate influences the metabolic activity of BAT (as assessed with a FDG-PET CT scan) in relation to hepatic and peripheral insulin sensitivity (2H2-glucose and [1,1,2,3,3-2H5]glycerol based two step…
To assess if treatment of an intermediate vulnerable coronary lesion in symptomatic patients using a BVS is feasible, results in a more stable plaque, increases vessel luminal area, preserves or improves vasomotion and is not associated with…
To examine the impact of prolonged (walking) exercise on cardiac and vascular function in older humans
To identify complement donors with no or low antibodies to Meningococcal strains to be used used as a complement source in SBAs against a panel of meningococci during evaluation of clinical trial samples
Our objective is to assess whether patients with SM compared to controls have more advanced atherosclerosis assessed by carotid intima-media thickness (C-IMT) and carotid plaques and have a more adverse cardiovascular risk profile.
This study will investigate the feasibility of a hypoxic challaenge test (60 minutes duration). During this test the inspired air will have a oxygen content of 15%. This is a comparable value as is used during a commercial airline flight (ca 2500…
The current study aims to evaluate the effectiveness of an individual online self-management program called *Partner in Balans* in increasing feelings of self-confidence and preventing depressive complaints in family caregivers of patients with (…
To investigate if the active product shows a postprandial plasma triglyceride profile different from the control product in healthy adult male volunteers.
To define the amount of dietary protein required to optimally stimulate post-exercise muscle protein synthesis in the older population.To assess whether co-ingesting 1.5 g of free leucine (contained within 15 g dairy protein) along with 15 g protein…
1. The primary efficacy objective is to evaluate whether rivaroxaban, in doses of 10 mg or 20 mg, is superior to ASA 100 mg in the prevention of the primary efficacy outcome (i.e. fatal or non-fatal symptomatic recurrent venous thromboembolism).2.…
To determine if maintenance therapy with AZN will provide significant improvements in PCD lung disease, compared to placebo: reduction in respiratory system exacerbations and improvement in lung function, ventilation inhomogeneity, improvement in…
Considering the background information given in the previous paragraph, the following research question has been formulated:What is the long-term (24 weeks) effect of magnesium citrate (total daily dose: 350 mg elemental magnesium) on vascular…
A promising strategy to reduce postlaparoscopic shoulder pain and abdominal pain is the pulmonary recruitment maneuver. By using manual pulmonary inflations, the intraperitoneal pressure increases and removal of residual carbon dioxide will be…