20 results
The primary objective of this study is to assess the comparative safety and efficacy ofAztreonam Lysine for Inhalation (AZLI) and Tobramycin Nebuliser Solution (TNS) in adultand pediatric cystic fibrosis (CF) patients aged 6 years or older with…
Primary objective: -to determine if there is a significant difference in the incidence of oxygen dependency at day 28 and/or death within the first 28 days of life between newborns with congenital diaphragmatic hernia treated with high frequency…
To establish the effect of BCG vaccination in 6 weeks old high-risk infants on the prevalence of asthma and allergic rhinitis at the age of 7 years.
Determining the prevalence of testicular microlithiasis in Down syndrome.
The purpose of this study is to evaluate in a Randomized Controlled Trial (RCT) study the effectiveness of AK alone and in combination with parent-management- training (PMT). The PMT component is added because parental involvement increases…
To decrease the incidence of sepsis after removal of central venous catheters in the neonatal intensive care unit.
Characterization of T cell responses in young children after influenza infection
The proposed RCT has as its goal to test the effectiveness of PMTO against Care As Usual (CAU).
To gain insight in the neural mechanisms underlying of the development of literacy.
Primary: Dose finding for a twice daily regimen for PSZ as prophylactic treatment in children with CGD, based on the exposure to PSZ measured by PSZ trough levels.Secondary:To determine the tolerability of PSZ as prophylactic treatment in children…
Primary:To determine trends in vaccine- and nonvaccine-serotype S. pneumoniae asymptomatic colonisation in healthy 11-month-old and 24-month-old infants who have been immunized according to the Dutch NIP with 7-valent pneumococcal conjugate vaccine…
The objective of this research is to develop a method which can identify among all consanguineous couples the ones which are at high risk.
1. To detrrmine the applicability of standard energy expenditure prediction equations for accelerometry in measuring physical activity in children with musculoskeletal and other chronic diseases (see below).2. To develop disease specific prediction…
The prime objective of this research project is to assess the feasibility of a low-threshold, accessible, preventive cognitive-behavioural therapeutic intervention with parental support for grieving children and their parents, and to get a first…
Developing an evidence-based guideline for the diagnosis and surgical treatment of children with severe gastro-esophageal reflux disease.
Objective of this study is the development of a national "best practice guideline on pre and postnatal follow up for prenatally detected abnormalities of the kidney and/or urinary tract". Furthermore, the guidelijne will be evaluated and…
To improve physical activity levels and physical activity patterns in children with JIA by means of cognitive behavioural training based on the social cognitive theory and the health promotion model, delivered by internet and supported by group…
The objectives are to:A. Identify subjects with VWD who may benefit from prophylaxis by determining patterns of bleeding prior to evaluation for enrollmentB. Study the effect of prophylaxis on bleeding frequencyC. Establish optimal treatment…
To identify serological correlates of protection against clinical measles and measles virus infection in once vaccinated children.
1) To examine the effect of a 12-week multidisciplinary treatment on endothelial function, intima-media thickness and blood cholesterol in obese children (8-17 years).2) Investigate the changes in vascular function in obese children (8-17 years).