125 results
The first part of this study (2017) aimed to explore perceptions of care and needs of support in a suicidal crisis of family members and suicidal patients (in current remission). These mapped experiences have contributed to an emerging theory to…
The purpose of the research trial is to assess if heart failure markers and clinical end-points are influenced by 24 hours of AV-node stimulation (AVNS) in acutely decompensated heart failure (ADHF) patients.Primary Objective(s)The primary objective…
The primary objective is to evaluate in the two targeted populations (i.e. CD and self-reported NCGS subjects):1) the safety profile of BL NCC 2705 2) the gastro-intestinal (GI) tolerability of BL NCC 2705
The primary objective is to test the hypothesis that galcanezumab is superior to placebo in the prevention of migraine in patients with treatment-resistant migraine.The key secondary objective are:- To compare galcanezumab with placebo with respect…
To determine the correlation between neurocognitive function and the incidence of DTI abnormalities on MRI in irradiated glioma patients.
Defining which sampling site in the mouth in infants and their mothers is most reproducible as determined by the differences in microbiota composition of samples collected by a trained researcher and those collected by the mother
The purpose of the overall project is to adapt an existing self management tool for adults to the needs of young people and how to implement the adapted app within the youth mental health. The overall project consists of three different phases with…
The main objective of the human dietary intervention study is to investigate the beneficial health effects of food products containing various combinations of an equivalent of 400 grams vegetables and fruits in healthy volunteers. This will be…
This study is designed to test the hypothesis that in-hospital dance courses are a feasible non-pharmacological intervention for improving quality of life in community-dwelling people with dementia. Current study is a pilot study, meaning it's…
The primary objective of this project is to map differences in joint loading between athletes receiving visual feedback and those who will not receive visual feedback in both retention and transfer to field-specific situations. From there. we will…
The primary objective is to determine feasibility of a home-based exercise program in a pilot study with patients with combined chronic pulmonary and cardiac disease.Secondary objectives are to evaluate patient satisfaction and changes in functional…
In the proposed project we evaluate the potential benefits and feasibility of including (a) a decision support system, *Clinical Rules Engine* (CRE) and (b) patient preferences, using the *Outcome Prioritization Tool* (OPT) in a comprehensive…
- The main objective of this study is to develop a predictive model that can estimate the rest energy expenditure in indviduals with SCI or LLA.- To develop a model based on raw accelerometry data that can estimate the energy expenditure during ADL…
Aim of the MIRRE pilot study is to determine how much the primary inoculation dose of diarrheagenic E. coli should be lowered in order to result in a reduced protective response upon a secondary infection.
1.3. Study Design Rationale The ATLAS-PPX trial (ALN-AT3SC-009) is a multicenter, multinational, open-label Phase 3 switching study designed to demonstrate the efficacy and safety of fitusiran in patients with hemophilia A or B, with inhibitory…
The aim of this study is to find a directly applicable intervention for acutely suicidal patients, so that the risk of these patients committing suicide is substantially lowered, leading to fewer actual suicides. To this end we propose a randomized…
The primary objectives are to evaluate preliminary data on the safety and performance of theEmboliner embolic protection catheter.Safety:Assess procedural safety risksPerformance:Assess the technical performance in conjunction with a TAVR procedure.
to evaluate the safety and efficacy of two different doses of a delayed release formulation of rifaximin (Rifaximin-EIR) for the prevention of recurrence of diverticulitis and diverticular complications in patients with a recent episode of…
Our primary objective is to enable rapid estimation of the current and future risks of importation into the Netherlands of majorarboviral Aedes-borne diseases (Dengue, Chikunguya, Zika and Yellow Fever viruses). The possibility of (re)establishment…
To get insights into how the composition of the meal can affect the effects of prolonged sitting and sitting interrupted with physical activity on cognitive function and other health outcomes.