1211 results
Primary:The primary objective is to evaluate the safety profile of an adjuvated Tb subunit vaccine (CAF01) administered in 50 µg Ag85B-Esat-6 alone, 50 µg Ag85B-Esat-6 alone with three escalating CAF01 dose levels, to four groups of healthy…
The aim of the current study is to:1. Determine the incidence of CIN after introduction of preventive measures.2. Describe changes in the course of biomarkers serum creatinine, microalbumin and microglobulin related to intravenous ICM administration…
The aim of the study is to compare magnesiumhydroxide and polyethylene glycol/electrolytes with regard to the prevention of constipation and side-effects in palliative care cancer patients starting with opioids.
This study will test the following hypotheses:Primary: The DirectLife program is effective in increasing the level of physical activity in an ageing populationSecondary:1. The level of physical activity associates with parameters of 24-hour glucose…
To investigate the effectiveness of an internet physical activity / self-management program (artroseinbeweging.nl).
To compare the efficacy of playing Tetris to Assessments Only in the reduction of frequency, vividness, and emotional intensity of intrusions in Dutch soldiers exposed to aversive events on deployment in Afghanistan.
The objective of this study is to develop a resistance training intervention that improves mobility and quality of life in diabetic patients. It is also our intension to achieve a better understanding of the relation between diabetic neuropathy and…
To determine whether fibrinogen concentrate infusion reduces perioperative blood loss and transfusion in patient experiencing clinically relevant microvascular bleeding during elective complex cardiac surgery and to determine whether its use is safe…
Primary ObjectivesThe primary objectives of this study are to establish:1. The efficacy of internet-delivered SMT for chronic migraine - compared to waitlist control- regarding the post-training improvement of migraine attacks and headache days per…
Tissue hypoxia occurs frequently during high-risk surgery in high-risk patients. We want to see if an algorithm aimed at optimizing intraoperative tissue oxygenation reduces perioperative complications as well as length of stay in the intensive care…
Our primary objective is to compare the short term (3 months follow-up) clinical and radiographic results of the Bledsoe Thruster Brace with the SofTec OA Brace in the management of patients with medial knee OA and a varus leg alignment.
Objective of the study is to test the effects of two different interventions during the nightshift on alertness and performance and on sleep quality and health complaints in general. The interventions are short exposure to light or taking a powernap…
Main objective is to investigate if low molecular weight fraction of edible mushroom Shiitake extract possesses clinically relevant caries preventive properties
This project focuses on injury prevention-related cost-effectiveness of the "F-MARC Bricks".We hypothesize that the exercises of the *F-MARC Bricks*, integrated in the warm up, reduce injury incidence and/or injury severity and…
The aim of the project is to further develop and study the effectiveness of the Internet groupcourse Gripop Je Dip Online for young people (16-25 years) with depressive symptoms.Development objective:The eight-session groupcourse will be adapted…
In this study we will be looking at the effects of the different administration routes on release of satiety hormones by the small intestine.
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
The primary aim of this study is to investigate if a tight multiple cardiovascular risk reduction program is effective in reducing progression of Intima media thickness progression (subclinical atherosclerosis) in patients with RA compared to usual…
The objective of this study is to determine whether the intake of protein with extra leucine or extra carbohydrates added results in an improved muscle protein synthesis compared to the intake of only protein in elderly.
Primary Objective: Comparison of incidence of post-cataract extraction ocular inflammation with subconjunctival steroid injection versus traditional eye drops.Secondary Objective: Evaluation of usefulness of physostigmine following cataract surgery.